A novel electrochemical sensor based on graphene nanosheets and ethyl 2-(4-ferrocenyl-[1,2,3]triazol-1-yl) acetate for electrocatalytic oxidation of cysteine and tyrosine

被引：21

作者：

Beitollahi, Hadi ^{[1
,2
]}

Ganjali, Mohammad Reza ^{[3
,4
]}

Norouzi, Parviz ^{[3
,4
]}

Movlaee, Kaveh ^{[3
]}

Hosseinzadeh, Rahman ^{[5
]}

Tajik, Somayeh ^{[1
,6
]}

机构：

[1] Bam Univ Med Sci, Bam, Iran

[2] Grad Univ Adv Technol, Inst Sci & High Technol & Environm, Environm Dept, Sci, Kerman, Iran

[3] Univ Tehran, Fac Chem, Ctr Excellence Electrochem, Tehran, Iran

[4] Univ Tehran Med Sci, Biosensor Res Ctr, Endocrinol & Metab Mol Cellular Sci Inst, Tehran, Iran

[5] Univ Mazandaran Babolsar, Fac Chem, Dept Organ Chem, Babol Sar, Iran

[6] Kerman Univ Med Sci, Res Ctr Trop & Infect Dis, Kerman, Iran

来源：

MEASUREMENT | 2020年 / 152卷

关键词：

Cysteine; Tyrosine; Ferrocene derivatives; Graphene; Electrochemical sensor; CARBON-PASTE ELECTRODE; SELECTIVE DETERMINATION; ASCORBIC-ACID; URIC-ACID; VOLTAMMETRIC DETERMINATION; NANOPARTICLES; NANOTUBES; BEHAVIOR; FILM; NOREPINEPHRINE;

D O I：

10.1016/j.measurement.2019.107302

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A novel electrochemical sensor based on ethyl 2-(4-ferrocenyl-[1,2,3]triazol-1-yl) acetate (EFTA) and graphene has been developed for electrocatalytic oxidation and determination of cysteine. The electrochemical behavior of cysteine at the EFTAGCPE was investigated by voltammetric techniques. The EFTAGCPE showed efficient electrocatalytic activity for the oxidation of cysteine in 0.1 M phosphate buffer solution (pH 7.0). The oxidation overpotential of cysteine decreased significantly compared with the bare electrode and its oxidation peak currents increased dramatically at EFTAGCPE. The potential utility of the sensor was demonstrated by applying it to the analytical determination of cysteine concentration. The results showed that the electrocatalytic current increased linearly with the cysteine concentration in the range of 4.0-2300.0 mu M and the detection limit was 0.9 mu M. Also the prepared modified electrode exhibits a very good resolution between the voltammetric peaks of cysteine and tyrosine. The sensor was applied to determine cysteine and tyrosine in human fluids samples. (C) 2019 Elsevier Ltd. All rights reserved.

引用

页数：6

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