Bradykinin B1 Receptor Antagonists as Potential Therapeutic Agents for Pain

被引：26

作者：

Huang, Hui ^{[1
]}

Player, Mark R. ^{[1
]}

机构：

[1] Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 2010年 / 53卷 / 15期

关键词：

B-1; RECEPTOR; P-GLYCOPROTEIN; KININ B-1; NONPEPTIDE ANTAGONISTS; STRUCTURE ELUCIDATION; INDUCED HYPERALGESIA; ANALGESIC EFFICACY; DRUG-INTERACTIONS; MESSENGER-RNA; SPINAL-CORD;

D O I：

10.1021/jm1000776

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：5383 / 5399

页数：17

共 110 条

[1] Peptide and non-peptide bradykinin receptor antagonists: Role in allergic airway disease [J].

Abraham, WM ;

Scuri, M ;

Farmer, SG .

EUROPEAN JOURNAL OF PHARMACOLOGY, 2006, 533 (1-3) :215-221

[2] B1 receptors as a new inflammatory target.: Could this B the 1? [J].

Ahluwalia, A ;

Perretti, M .

TRENDS IN PHARMACOLOGICAL SCIENCES, 1999, 20 (03) :100-104

[3] Efficacy and tolerability of Icatibant (Hoe 140) in patients with moderately severe chronic bronchial asthma [J].

Akbary, AM ;

Wirth, KJ ;

Scholkens, BA .

IMMUNOPHARMACOLOGY, 1996, 33 (1-3) :238-242

[4] Effect of high salt intake in mutant mice lacking bradykinin-B-2 receptors [J].

Alfie, ME ;

Sigmon, DH ;

Pomposiello, SI ;

Carretero, OA .

HYPERTENSION, 1997, 29 (01) :483-487

[5] Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction [J].

Bertilsson, G ;

Heidrich, J ;

Svensson, K ;

Åsman, M ;

Jendeberg, L ;

Sydow-Bäckman, M ;

Ohlsson, R ;

Postlind, H ;

Blomquist, P ;

Berkenstam, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (21) :12208-12213

[6] Aryl sulfones as novel Bradykinin B1 receptor antagonists for treatment of chronic pain [J].

Biswas, Kaustav ;

Aya, Toshihiro ;

Qian, Wenyuan ;

Peterkin, Tanya A. N. ;

Chen, Jian Jeffrey ;

Human, Jason ;

Hungate, Randall W. ;

Kumar, Gondi ;

Arik, Leyla ;

Lester-Zeiner, Dianna ;

Biddlecome, Gloria ;

Manning, Barton H. ;

Sun, Hong ;

Dong, Hong ;

Huang, Ming ;

Loeloff, Richard ;

Johnson, Eileen J. ;

Askew, Benny C. .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (17) :4764-4769

[7] Potent nonpeptide antagonists of the bradykinin B1 receptor: Structure-activity relationship studies with novel diaminochroman carboxamides [J].

Biswas, Kaustav ;

Li, Aiwen ;

Chen, Jian Jeffrey ;

D'Amico, Derin C. ;

Fotsch, Christopher ;

Han, Nianhe ;

Human, Jason ;

Liu, Qingyian ;

Norman, Mark H. ;

Riahi, Bobby ;

Yuan, Chester ;

Suzuki, Hideo ;

Mareska, David A. ;

Zhan, James ;

Clarke, David E. ;

Toro, Andras ;

Groneberg, Robert D. ;

Burgess, Laurence E. ;

Lester-Zeiner, Dianna ;

Biddlecome, Gloria ;

Manning, Barton H. ;

Arik, Leyla ;

Dong, Hong ;

Huang, Ming ;

Kamassah, Augustus ;

Loeloff, Richard ;

Sun, Hong ;

Hsieh, Feng-Yin ;

Kumar, Gondi ;

Ng, Gordon Y. ;

Hungate, Randall W. ;

Askew, Benny C. ;

Johnson, Eileen .

JOURNAL OF MEDICINAL CHEMISTRY, 2007, 50 (09) :2200-2212

[8] The kallikrein-kininogen-kinin system: lessons from the quantification of endogenous kinins [J].

Blais, C ;

Marceau, F ;

Rouleau, JL ;

Adam, A .

PEPTIDES, 2000, 21 (12) :1903-1940

[9] L-745,337 - A SELECTIVE INHIBITOR OF CYCLOOXYGENASE-2 ELICITS ANTINOCICEPTION BUT NOT GASTRIC-ULCERATION IN RATS [J].

BOYCE, S ;

CHAN, CC ;

GORDON, R ;

LI, CS ;

RODGER, IW ;

WEBB, JK ;

RUPNIAK, NMJ ;

HILL, RG .

NEUROPHARMACOLOGY, 1994, 33 (12) :1609-1611

[10] Effect of Bradykinin receptor antagonists on vincristine- and streptozotocin-induced hyperalgesia in a rat model of chemotherapy-induced and diabetic neuropathy [J].

Bujalska, Magdalena ;

Tatarkiewicz, Jan ;

Gumulka, Stanislaw Witold .

PHARMACOLOGY, 2008, 81 (02) :158-163

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