Redox-Neutral Indole Annulation Cascades

被引：178
作者：
Haibach, Michael C. [1 ]
Deb, Indubhusan [1 ]
De, Chandra Kanta [1 ]
Seidel, Daniel [1 ]
机构：
[1] Rutgers State Univ, Dept Chem & Chem Biol, Piscataway, NJ 08854 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 133卷 / 07期
基金：
美国国家科学基金会;
关键词：
C-H BOND; RING-CLOSURE REACTIONS; NITROGEN-CONTAINING HETEROCYCLES; ONE-POT SYNTHESIS; INTERMOLECULAR REACTIONS; CYCLOADDITION REACTION; CATALYZED CYCLIZATION; 1,5-HYDRIDE SHIFTS; ORGANIC-SYNTHESIS; ALKYNYL ETHERS;
D O I：
10.1021/ja110713k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Aminobenzaldehydes react with indoles in an unprecedented cascade reaction. This acid-catalyzed redox-neutral annulation proceeds via a condensation/1,5-hydride shift/ring-closure sequence. Polycyclic azepinoindoles and related compounds are obtained in a single step with good to excellent yields.
引用
收藏
页码：2100 / 2103
页数：4
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