Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts

被引：955
|
作者：
Vakulya, B
Varga, S
Csámpai, A
Soós, T
机构：
[1] Hungarian Acad Sci, Chem Res Ctr, Inst Biomol Chem, H-1525 Budapest, Hungary
[2] Eotvos Lorand Univ, Dept Gen & Inorgan Chem, H-1518 Budapest, Hungary
来源：
ORGANIC LETTERS | 2005年 / 7卷 / 10期
关键词：
D O I：
10.1021/ol050431s
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.
引用
收藏
页码：1967 / 1969
页数：3
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