Gene expression profiling of endocrine tumors using DNA microarrays: Progress and promise

被引:15
作者
Giordano, TJ
机构
[1] Univ Michigan, Hlth Syst, Dept Pathol, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Hlth Syst, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA
关键词
gene expression; molecular classification; tissue array; biomarker;
D O I
10.1385/EP:14:2:107
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Genomewide profiling of gene expression, made possible by the development of DNA microarray technology and more powerful by the sequencing of the human genome, has led to advances in tumor classification and biomarker discovery for the common types of human neoplasia. Application of this approach to the field of endocrine neoplasia is in its infancy, although some progress has been recently reported. In this review, the progress to date is summarized and the promise of DNA microarray analysis in conjunction with tissue array immunohistochemistry to significantly impact endocrine tumor diagnosis and prognosis is discussed.
引用
收藏
页码:107 / 116
页数:10
相关论文
共 49 条
[1]  
Aljundi RT, 2003, MODERN PATHOL, V16, p102A
[2]   Microarrays: the use of oligonucleotides and cDNA for the analysis of gene expression [J].
Barrett, JC ;
Kawasaki, ES .
DRUG DISCOVERY TODAY, 2003, 8 (03) :134-141
[3]   Gene-expression profiles predict survival of patients with lung adenocarcinoma [J].
Beer, DG ;
Kardia, SLR ;
Huang, CC ;
Giordano, TJ ;
Levin, AM ;
Misek, DE ;
Lin, L ;
Chen, GA ;
Gharib, TG ;
Thomas, DG ;
Lizyness, ML ;
Kuick, R ;
Hayasaka, S ;
Taylor, JMG ;
Iannettoni, MD ;
Orringer, MB ;
Hanash, S .
NATURE MEDICINE, 2002, 8 (08) :816-824
[4]   Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses [J].
Bhattacharjee, A ;
Richards, WG ;
Staunton, J ;
Li, C ;
Monti, S ;
Vasa, P ;
Ladd, C ;
Beheshti, J ;
Bueno, R ;
Gillette, M ;
Loda, M ;
Weber, G ;
Mark, EJ ;
Lander, ES ;
Wong, W ;
Johnson, BE ;
Golub, TR ;
Sugarbaker, DJ ;
Meyerson, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (24) :13790-13795
[5]   Minimum information about a microarray experiment (MIAME) - toward standards for microarray data [J].
Brazma, A ;
Hingamp, P ;
Quackenbush, J ;
Sherlock, G ;
Spellman, P ;
Stoeckert, C ;
Aach, J ;
Ansorge, W ;
Ball, CA ;
Causton, HC ;
Gaasterland, T ;
Glenisson, P ;
Holstege, FCP ;
Kim, IF ;
Markowitz, V ;
Matese, JC ;
Parkinson, H ;
Robinson, A ;
Sarkans, U ;
Schulze-Kremer, S ;
Stewart, J ;
Taylor, R ;
Vilo, J ;
Vingron, M .
NATURE GENETICS, 2001, 29 (04) :365-371
[6]   The use and analysis of microarray data [J].
Butte, A .
NATURE REVIEWS DRUG DISCOVERY, 2002, 1 (12) :951-960
[7]   Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays [J].
Cai, WW ;
Mao, JH ;
Chow, CW ;
Damani, S ;
Balmain, A ;
Bradley, A .
NATURE BIOTECHNOLOGY, 2002, 20 (04) :393-396
[8]   Mapping and sequencing chromosome breakpoints [J].
Carter, NP .
CYTOMETRY, 2002, :43-43
[9]   Discordant protein and mRNA expression in lung adenocarcinomas [J].
Chen, GA ;
Gharib, TG ;
Huang, CC ;
Taylor, JMG ;
Misek, DE ;
Kardia, SLR ;
Giordano, TJ ;
Iannettoni, MD ;
Orringer, MB ;
Hanash, SM ;
Beer, DG .
MOLECULAR & CELLULAR PROTEOMICS, 2002, 1 (04) :304-313
[10]   Making and reading microarrays [J].
Cheung, VG ;
Morley, M ;
Aguilar, F ;
Massimi, A ;
Kucherlapati, R ;
Childs, G .
NATURE GENETICS, 1999, 21 (Suppl 1) :15-19