Long term use of bevacizumab in the treatment of triple negative breast cancer with giant tumor in chest wall A case report

被引：7

作者：

Gui, Xinyu ^{[1
]}

Li, Huiping ^{[1
]}

Song, Guohong ^{[1
]}

Shao, Bin ^{[1
]}

Jiang, Hanfang ^{[1
]}

机构：

[1] Peking Univ, Canc Hosp & Inst, Key Lab Carcinogenesis & Translat Res, Minist Educ Beijing,Dept Breast Oncol, Beijing, Peoples R China

来源：

MEDICINE | 2018年 / 97卷 / 48期

关键词：

bevacizumab; breast cancer; chest wall metastasis; triple negative; CONTAINING THERAPY; ANGIOGENESIS; METASTASIS; RECEPTORS;

D O I：

10.1097/MD.0000000000013410

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Rationale: Triple-negative breast cancer (TNBC) is associated with unfavorable prognosis due to lack of targeted agents. Bevacizumab, an anti-angiogenic monoclonal antibody against vascular endothelial growth factor A, has shown clinical effects in patients with TNBC. Patient concerns: We reported a 49-year-old woman presenting with a giant breast tumor. Diagnoses: Stage IV TNBC with chest wall metastasis. Interventions: The patient underwent long-term use of bevacizumab combined with chemotherapy. Outcomes: The patient was on follow-up for 46 months, a remarkable improvement of the chest wall cutaneous lesion was observed. Lessons: Bevacizumab may provide benefits for TNBC patients with chest wall metastasis.

引用

页数：3

共 17 条

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