Insights from nanomedicine into chloroquine efficacy against COVID-19

被引:209
作者
Hu, Tony Y. [1 ]
Frieman, Matthew [2 ]
Wolfram, Joy [3 ,4 ,5 ,6 ]
机构
[1] Tulane Univ, Sch Med, Dept Biochem & Mol Biol, Ctr Cellular & Mol Diagnost, 1430 Tulane Ave, New Orleans, LA 70112 USA
[2] Univ Maryland, Sch Med, Dept Microbiol & Immunol, Baltimore, MD 21201 USA
[3] Mayo Clin, Dept Biochem & Mol Biol, Jacksonville, FL 32224 USA
[4] Mayo Clin, Dept Physiol & Biomed Engn, Jacksonville, FL 32224 USA
[5] Mayo Clin, Dept Transplantat, Jacksonville, FL 32224 USA
[6] Houston Methodist Res Inst, Dept Nanomed, Houston, TX USA
基金
美国国家卫生研究院;
关键词
CORONAVIRUS; INFECTION; RECEPTOR; ENTRY; CELLS;
D O I
10.1038/s41565-020-0674-9
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Chloroquine - an approved malaria drug - is known in nanomedicine research for the investigation of nanoparticle uptake in cells, and may have potential for the treatment of COVID-19.
引用
收藏
页码:247 / 249
页数:3
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