Microwave-Assisted Debromination of α-Bromoketones with Triarylstibanes in Water

被引：0

作者：

Murata, Yuki ^{[1
]}

Sugawara, Yoshiyuki ^{[2
]}

Matsumura, Mio ^{[1
]}

Kakusawa, Naoki ^{[2
]}

Yasuike, Shuji ^{[1
]}

机构：

[1] Aichi Gakuin Univ, Sch Pharmaceut Sci, Chikusa Ku, 1-100 Kusumoto Cho, Nagoya, Aichi 4648650, Japan

[2] Hokuriku Univ, Fac Pharmaceut Sci, Ho 3 Kanagawa Machi, Kanazawa, Ishikawa 9201181, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2017年 / 65卷 / 11期

关键词：

microwave; debromination; alpha-bromoketone; triarylstibane; water; HALO CARBONYL-COMPOUNDS; ORGANIC-SYNTHESIS; REDUCTIVE DEHALOGENATION; ORGANOANTIMONY COMPOUNDS; TRANSMETALLATING AGENT; TERTIARY STIBINE; KETONES; ALDEHYDES; HALIDES; LIGAND;

D O I：

10.1248/cpb.c17-00533

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Several alpha-bromoarylketones were reacted with triarylstibanes under microwave irradiation in water to obtain the corresponding debrominated ketones. Under similar reaction conditions, 1,2-elimination of vicdibromides in water afforded the corresponding E-olefins. This reaction is the first example of organoantimony compounds utilized for organic transformation in water.

引用

页码：1081 / 1084

页数：4

共 42 条

[1] DEBROMINATION OF PHENACYL AND BENZYLIC BROMIDES WITH TERTIARY STIBINE AND THE MECHANISTIC CONSIDERATION [J].