Linitis plastica

被引:10
作者
Beyrouti, Mohamed Issam [1 ]
Beyrouti, Ramez [1 ]
Ben Amar, Mohamed [1 ]
Frikha, Foued [1 ]
Beyrouti, Rahma [1 ]
Abid, Mohamed [1 ]
Ben Salah, Khalil [1 ]
Boujelben, Salah [1 ]
机构
[1] EPS Habib Bourguiba, Serv Chirurg Gen, Sfax 3029, Tunisia
来源
PRESSE MEDICALE | 2007年 / 36卷 / 12期
关键词
D O I
10.1016/j.lpm.2007.03.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Linitis plastica accounts for 3-19% of gastric cancers. Its diagnosis requires morphology findings of on infiltrating stomach tumor and pathology findings including signet-ring cells and fibrous stroma. Its etiology is not known, and it has no particular features. Diagnostic sensitivity of endoscopy is poor because of the difficulty of biopsies: "Forceps slide on the infiltrated walls." Its characteristic radiologic appearance is due to the infiltration and stiffness that causes it to be known as "leather-bottle Stomach". Endosonography is currently the reference examination and has made it possible to identify localized linitis. Unlike other stomach cancers, it frequently extends into the peritoneum and lymphatic system. Curative treatment remains radical surgical resection. Modern chemotherapy protocols based on oral derivatives of 5-FU (TS-1) and of paclitaxel appear promising. The severity of its prognosis is explained by the frequency of peritoneal dissemination, lymphatic invasion and extension toward neighboring organs.
引用
收藏
页码:1782 / 1786
页数:5
相关论文
共 31 条
[1]  
ABDU RA, 1993, ARCH SURG-CHICAGO, V128, P103
[2]   CT IN PATIENTS WITH SCIRRHOUS CARCINOMA OF THE GI TRACT - IMAGING FINDINGS AND VALUE FOR TUMOR-DETECTION AND STAGING [J].
BALTHAZAR, EJ ;
SIEGEL, SE ;
MEGIBOW, AJ ;
SCHOLES, J ;
GORDON, R .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1995, 165 (04) :839-845
[3]  
Berrada S, 1996, ANN GASTROENT HEPATO, V32, P120
[5]  
DUCREUX M, 2000, HEPATO GASTRO, V4, P263
[6]   A new mutation of E-cadherin gene in familial gastric linitis plastica cancer with extra-digestive dissemination [J].
Dussaulx-Garin, L ;
Blayau, M ;
Pagenault, M ;
Le Berre-Heresbach, N ;
Raoul, JL ;
Campion, JP ;
David, V ;
Bretagne, JF .
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2001, 13 (06) :711-715
[7]  
EIGO O, 2004, AM J SURG, V188, P327
[8]  
Ferri LE, 1999, CAN J SURG, V42, P466
[9]  
GUEZ C, 1993, GASTROEN CLIN BIOL, V17, P599
[10]  
Hamy A, 1999, INT SURG, V84, P337