aMAGEing New Players Enter the RING to Promote Ubiquitylation

被引：13

作者：

Espantman, Kristen C. ^{[1
]}

O'Shea, Clodagh C. ^{[1
]}

机构：

[1] Salk Inst Biol Studies, Mol & Cell Biol Lab, La Jolla, CA 92037 USA

来源：

MOLECULAR CELL | 2010年 / 39卷 / 06期

关键词：

APOPTOSIS; PROTEINS; FAMILY; KAP1;

D O I：

10.1016/j.molcel.2010.09.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The MAGE proteins are best known as curious tumor-specific antigens. However, Doyle et al. (2010) reveal that MAGE proteins interact with RING proteins to promote ubiquitylation which provides important new insights into the physiological and pathological functions of this enigmatic family of proteins.

引用

页码：835 / 837

页数：3

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