Antiplatelet Therapy in Acute Coronary Syndromes

被引：9

作者：

Aragam, Krishna G. ^{[3
]}

Bhatt, Deepak L. ^{[1
,2
]}

机构：

[1] Brigham & Womens Hosp, VA Boston Healthcare Syst, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Boston, MA USA

[3] Univ Michigan, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS | 2011年 / 16卷 / 01期

关键词：

acute coronary syndrome; antiplatelet therapy; aspirin; clopidogrel; glycoprotein IIb/ IIIa inhibitor; ELEVATION MYOCARDIAL-INFARCTION; OPTIMIZING PLATELET INHIBITION; DOUBLE-BLIND; UNSTABLE ANGINA; RECEPTOR ANTAGONIST; HEART-ASSOCIATION; AMERICAN-COLLEGE; STENT THROMBOSIS; CARDIOVASCULAR ANGIOGRAPHY; PREMATURE DISCONTINUATION;

D O I：

10.1177/1074248410381758

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Antiplatelet therapy is integral to the acute and long-term management of acute coronary syndromes (ACSs) and for minimizing the thrombotic complications of percutaneous coronary intervention (PCI). This article reviews the most commonly used antiplatelet agents in ACS therapy-aspirin, adenosine diphosphate (ADP)-receptor blockers, and glycoprotein IIb/IIIa inhibitors. More recent data are also reviewed on novel ADP-receptor blockers and thrombin inhibitors before addressing issues of adherence to antiplatelet regimens.

引用

页码：24 / 42

页数：19

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