Potentially bioactive two new natural sesquiterpenoids from the rhizomes of zingiber zerumbet

被引：15

作者：

Jang, DS

Seo, EK ^{[1
]}

机构：

[1] Ewha Womans Univ, Coll Pharm, Nat Prod Chem Lab, Seoul 120750, South Korea

[2] Korea Inst Oriental Med, Dept Herbal Pharmaceut Dev, Taejon 305811, South Korea

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2005年 / 28卷 / 03期

关键词：

Zingiber zerumbet; zingiberaceae; sesquiterpenoids; 6-methoxy-2E; 9E-humula-dien-8-one; stigmast-4-en-3-one;

D O I：

10.1007/BF02977795

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Repeated chromatography of the n-hexane-soluble fraction of the MeOH extract of the rhizomes of Zingiber zerumbet led to the isolation of two isomers of 6-methoxy-2E,9E-humula-dien-8-one (11 and 2) and stigmast-4-en-3-one. The structures of 1 and 2 were determined by spectroscopic methods including 1 D and 2D-NMR elucidated by analysis of spectroscopic data as well as by comparison with published values. This is the first report on the isolation of compounds I and 2 from the nature. Stigmast-4-en-3-one was first isolated from this plant.

引用

收藏

页码：294 / 296

页数：3

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