Prediction of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma by Using Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio

被引：33

作者：

Ozgonul, Cem ^{[1
]}

Sertoglu, Erdim ^{[2
]}

Mumcuoglu, Tarkan ^{[3
]}

Ozge, Gokhan ^{[3
]}

Gokce, Gokcen ^{[4
]}

机构：

[1] Van Mil Hosp, Dept Ophthalmol, Van, Turkey

[2] Ankara Mevki Mil Hosp, Biochem Lab, Anittepe Dispensary, Ankara, Turkey

[3] Gulhane Mil Med Acad, Dept Ophthalmol, Ankara, Turkey

[4] Kayseri Mil Hosp, Dept Ophthalmol, Kayseri, Turkey

来源：

OCULAR IMMUNOLOGY AND INFLAMMATION | 2016年 / 24卷 / 06期

关键词：

Glaucoma; inflammation; neutrophil to lymphocyte ratio; platelet to lymphocyte ratio; pseudoexfoliation syndrome; AQUEOUS-HUMOR; EXFOLIATION SYNDROME; TO-LYMPHOCYTE; GROWTH-FACTOR; MARKER;

D O I：

10.3109/09273948.2015.1063671

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To assess the levels of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with pseudoexfoliation syndrome (PEX) and to compare the NLR and PLR results of patients with PEX, PEX glaucoma (PXG), and healthy controls. Methods: In total, 34 patients with PEX, 29 patients with PXG, and 42 healthy subjects were enrolled in this retrospective study. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within 2 h of blood collection. Results: There was a significant difference in NLR between PEX and control groups (p = 0.012) and PXG and control groups (p = 0.003). Also, a significant difference was found in PLR values between control and PXG groups (p = 0.024). Conclusions: Our study for the first time provides evidence that PLR and NLR may be useful for predicting the prognosis of PEX patients and progression to PXG.

引用

页码：665 / 670

页数：6

共 24 条

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