Highly regioselective and diastereoselective epoxidation of allylic amines with Oxone

被引：26

作者：

Aggarwal, VK ^{[1
]}

Fang, GY ^{[1
]}

机构：

[1] Univ Bristol, Dept Chem, Bristol BS8 1TS, Avon, England

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 27期

关键词：

D O I：

10.1039/b503516c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Allylic amines ( as their protonated ammonium salts) can be epoxidised with high syn diastereoselectivity and regioselectivity at the proximal alkene in substrates with several double bonds using Oxone. The protonated ammonium cation activates the Oxone by hydrogen bonding, thus promoting the oxidation of groups within the vicinity of the complex.

引用

页码：3448 / 3450

页数：3

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