Nonprofit drugs as the salvation of the world's healthcare systems: the case of Antabuse (disulfiram)

被引：100

作者：

Cvek, Boris ^{[1
]}

机构：

[1] Palacky Univ, Dept Cell Biol & Genet, Olomouc 78371, Czech Republic

来源：

DRUG DISCOVERY TODAY | 2012年 / 17卷 / 9-10期

关键词：

BREAST-CANCER; VISCERAL LEISHMANIASIS; DIETHYLDITHIOCARBAMATE THERAPY; INHIBITION; PROTEASOME; DITIOCARB; PATIENT;

D O I：

10.1016/j.drudis.2011.12.010

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The effort to repurpose old drugs for new uses is not sufficient; even drugs that have been used clinically for decades must undergo expensive clinical trials. This process requires the pharmaceutical industry to fund the repatenting of old drugs. Because inexpensive drugs are necessary for people around the world, attempts should be made to develop nonprofit drugs through clinical trials of generic drugs that are funded by governments and charities. Evidence supports the use the old anti-alcoholic drug Antabuse as a new nonprofit drug for cancer.

引用

页码：409 / 412

页数：4

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