Crisaborole Ointment Effect on Global Atopic Dermatitis Severity and Early Relief in Pruritus: Pooled Results From Two Phase 3 Clinical Trials

被引:0
作者
Paller, Amy S. [1 ]
Yosipovitch, Gil [2 ]
Tom, Wynnis L. [3 ,4 ]
Lebwohl, Mark [5 ]
Boguniewicz, Mark [6 ,7 ]
Call, Robert S. [8 ]
Eichenfield, Lawrence F. [3 ,4 ]
Forsha, Douglass W. [9 ]
Rees, William C. [10 ]
Simpson, Eric L. [11 ]
Gold, Linda F. Stein [12 ]
Zaenglein, Andrea L. [13 ]
Tallman, Anna M. [14 ]
Tan, Bill [14 ]
Hebert, Adelaide A. [15 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
[2] Univ Miami, Miller Sch Med, Miami, FL 33136 USA
[3] Rady Childrens Hosp San Diego, San Diego, CA USA
[4] Univ Calif San Diego, San Diego, CA 92103 USA
[5] Icahn Sch Med Mt Sinai, New York, NY 10029 USA
[6] Natl Jewish Hlth, Denver, CO USA
[7] Univ Colorado, Sch Med, Denver, CO USA
[8] Clin Res Partners, Richmond, VA USA
[9] Jordan Valley Dermatol & Res Ctr, W Jordan, UT USA
[10] PI Coor Clin Res, Burke, VA USA
[11] Oregon Hlth & Sci Univ, Portland, OR 97201 USA
[12] Henry Ford Hlth Syst, Detroit, MI USA
[13] Penn State Univ, Hershey, PA USA
[14] Pfizer Inc, New York, NY USA
[15] Univ Texas Houston, Med Ctr, Houston, TX USA
关键词
D O I
10.1542/peds.142.1_MeetingAbstract.815
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
815
引用
收藏
页数:2
相关论文
共 50 条
[41]   Peak Pruritus Numeric Rating Scale response with abrocitinib in patients with moderate to severe atopic dermatitis: Results from a randomized phase 3 clinical trial [J].
Simpson, Eric L. ;
Staender, Sonja ;
Yosipovitch, Gil ;
Cameron, Michael C. ;
DiBonaventura, Marco ;
Williams, David ;
Tatulych, Svitlana ;
Nduaka, Chudy ;
Valdez, Hernan .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2020, 83 (06) :AB61-AB61
[42]   Efficacy of ruxolitinib cream for the treatment of atopic dermatitis by baseline clinical characteristics: Pooled subgroup analysis from two randomized phase 3 studies [J].
Papp, Kim ;
Szepietowski, Jacek C. ;
Kircik, Leon ;
Toth, Darryl ;
Eichenfield, Lawrence F. ;
Forman, Seth B. ;
Thaci, Diamant ;
Kuligowski, Michael E. ;
Venturanza, May E. ;
Sun, Kang ;
Simpson, Eric L. .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2021, 85 (03) :AB160-AB160
[43]   Tirbanibulin Ointment (1%) for the Treatment of actinic Keratoses (AK): pooled Data from two pivotal Phase III Clinical Trials [J].
Szeimies, R. M. ;
Dirschka, T. ;
Ocker, W. G. ;
Melzer, A. .
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2021, 19 :43-43
[44]   Safety and tolerability of fentanyl sublingual spray during the titration phase of two phase 3 clinical trials: results from pooled data [J].
Rauck, R. ;
Stearns, L. ;
Forman, N. ;
Parikh, N. ;
Dillaha, L. .
JOURNAL OF PAIN, 2014, 15 (04) :S67-S67
[45]   EVALUATING THE SEVERITY OF ATOPIC DERMATITIS (AD) IN CHILDREN AND ADULTS: MAPPING OF INVESTIGATOR'S STATIC GLOBAL ASSESSMENT (ISGA) TO ECZEMA AREA AND SEVERITY INDEX (EASI) IN PHASE 3 STUDIES OF CRISABOROLE, 2% [J].
Thyssen, J. P. ;
Zang, C. ;
Neary, M. P. ;
Bushmakin, A. G. ;
Cappelleri, J. ;
Cha, A. ;
Russo, C. ;
Luger, T. .
VALUE IN HEALTH, 2020, 23 :S520-S520
[46]   Effects of ruxolitinib cream in patients with atopic dermatitis with baseline body surface area ≥10% and Eczema Area and Severity Index score ≥16: Pooled results from two phase 3 studies [J].
Simpson, Eric L. ;
Kircik, Leon ;
Blauvelt, Andrew ;
Kuligowski, Michael E. ;
Venturanza, May E. ;
Sun, Kang ;
Eichenfield, Lawrence F. .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2021, 85 (03) :AB157-AB157
[47]   Rapid and early onset of itch relief with tapinarof cream 1% once daily in two pivotal phase 3 trials in adults and children down to two years of age with atopic dermatitis [J].
Simpson, Eric ;
Silverberg, Jonathan, I ;
Bissonnette, Robert ;
Gold, Linda Stein ;
Armstrong, April ;
Hebert, Adelaide A. ;
Serrao, Rocco T. ;
Jakus, Jeannette R. ;
Brown, Philip M. ;
Rubenstein, David S. ;
Piscitelli, Stephen C. ;
Tallman, Anna M. ;
Eichenfield, Lawrence F. .
BRITISH JOURNAL OF DERMATOLOGY, 2024, 190 :II18-II19
[48]   Rimegepant 75 mg Provides Early and Sustained Relief of Migraine With a Single Dose: Results from 3 Phase 3 Clinical Trials [J].
Pavlovic, Jelena ;
Dodick, David ;
Friedman, Deborah ;
Tepper, Stewart ;
Newman, Lawrence ;
Lipton, Richard ;
Stock, Elyse ;
Thiry, Alexandra ;
Conway, Charles ;
Jensen, Christopher ;
Morris, Beth ;
Coric, Vladimir ;
Croop, Robert .
NEUROLOGY, 2020, 94 (15)
[49]   FAVORABLE SAFETY PROFILE OF TIRBANIBULIN 1% OINTMENT FOR ACTINIC KERATOSIS: POOLED RESULTS FROM TWO PHASE 3 STUDIES [J].
Du Jardin, Kristian Gaarn ;
Schlesinger, Todd ;
Bhatia, Neal ;
Berman, Brian ;
Padulles, Laura ;
Cutler, David ;
Lebwohl, Mark .
ACTA DERMATO-VENEREOLOGICA, 2022, 102 :30-30
[50]   Effect of Ustekinumab on cardiovascular events: Results from pooled Phase 2 and 3 psoriasis trials [J].
Gordon, K. ;
Szapary, P. ;
Langley, R. G. ;
Reich, K. ;
Lebwohl, M. ;
Guzzo, C. ;
Yeilding, N. ;
Li, S. ;
Hsu, M. -C. ;
Griffiths, C. E. M. .
AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2011, 52 :26-27