Detection of human bocavirus in Saudi healthy blood donors

被引:13
作者
Abdel-Moneim, Ahmed S. [1 ,2 ]
Mahfouz, Mohammad E. [3 ,4 ]
Zytouni, Dalia M. [4 ]
机构
[1] Taif Univ, Coll Med, Dept Microbiol, Al Taif, Saudi Arabia
[2] Beni Suef Univ, Fac Vet Med, Virol Dept, Bani Suwayf, Egypt
[3] Taif Univ, Coll Med, Dept Surg, Al Taif, Saudi Arabia
[4] King Faisal Hosp, Al Taif, Saudi Arabia
关键词
HUMAN-IMMUNODEFICIENCY-VIRUS; HUMAN PARVOVIRUSES; PLASMA; GENOTYPE-1; PARV4;
D O I
10.1371/journal.pone.0193594
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Human bocavirus is associated with respiratory disease worldwide, mainly in children. There are conflicting results, however, regarding the existence of the HBoV in blood donors. Three hundred whole blood samples from non-immunodeficient healthy blood donors were screened for the presence of HBoV by polymerase chain reaction. The HBoV genotype of positive samples was determined using direct gene sequencing. Twenty-one out of the three hundred blood samples were found to be positive for HBoV. Sequence analysis of the positive samples revealed that all the strains were related to the HBoV-1 type with a low rate of variation among the detected sequences. It was concluded that there is a considerable risk of contracting HBoV from a blood transfusion from normal healthy individuals.
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页数:7
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