The Association of Non-Cardiac ECMO With Influenza Incidence: A Time Series Analysis

被引:1
作者
Insel, Michael [1 ]
Natt, Bhupinder [1 ]
Mosier, Jarrod [2 ]
Malo, Joshua [1 ]
Bime, Christian [1 ]
机构
[1] Univ Arizona Hlth Sci, Div Pulm Allergy Crit Care & Sleep Med, Tucson, AZ USA
[2] Univ Arizona, Coll Med, Dept Emergency Med, Tucson, AZ 85724 USA
关键词
acute respiratory distress syndrome; influenza virus; ECMO; epidemiology; H1N1; virus; adults; EXTRACORPOREAL MEMBRANE-OXYGENATION; ACUTE MYOCARDIAL-INFARCTION;
D O I
10.4187/respcare.06145
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
BACKGROUND: The 2009 H1N1 influenza epidemic saw a rise in the use of extracorporeal membrane oxygenation (ECMO) as a supportive therapy for refractory ARDS. We sought to determine whether ECMO utilization follows a seasonal pattern that matches the influenza season, and whether it can further be explained by the incidence of each influenza subtype. METHODS: We performed a longitudinal analysis of non-cardiac and cardiac-associated ECMO cases from the National In-patient Sample from 2005 to 2014, using overdispersed Poisson regression to evaluate associations with influenza incidence categorized by influenza-like illness and total positive influenza tests divided by subtype from the Centers for Disease Control and Prevention. RESULTS: Non-cardiac ECMO use was positively associated with influenza-like illness incidence in the current month (incidence risk ratio [IRR] 1.11, 95% confidence interval [CI] 1.07-1.15, P < .001) and with influenza-like illness in the previous month (IRR 1.09, 95% CI 1.05-1.14, P < .001). The 2009 H1N1 subtype had the strongest association with non-cardiac ECMO (IRR 1.19, 95% CI 1.09-1.31, P < .001). Cardiac ECMO was also positively associated with the incidence of influenza-like illness (IRR 1.05, 95% CI 1.01-1.09, P = .02). CONCLUSION: Non-cardiac and cardiac ECMO use in the United States were significantly associated with influenza incidence. The influenza A, H1N1 2009, subtype had the strongest association.
引用
收藏
页码:279 / 284
页数:6
相关论文
共 12 条
  • [1] Extracorporeal membrane oxygenation for respiratory failure in adults
    Combes, Alain
    Bacchetta, Matthew
    Brodie, Daniel
    Mueller, Thomas
    Pellegrino, Vince
    [J]. CURRENT OPINION IN CRITICAL CARE, 2012, 18 (01) : 99 - 104
  • [2] Extracorporeal Membrane Oxygenation for 2009 Influenza A(H1N1) Acute Respiratory Distress Syndrome
    Davies, Andrew
    Jones, Daryl
    Bailey, Michael
    Beca, John
    Bellomo, Rinaldo
    Blackwell, Nikki
    Forrest, Paul
    Gattas, David
    Granger, Emily
    Herkes, Robert
    Jackson, Andrew
    McGuinness, Shay
    Nair, Priya
    Pellegrino, Vincent
    Pettilae, Ville
    Plunkett, Brian
    Pye, Roger
    Torzillo, Paul
    Webb, Steve
    Wilson, Michael
    Ziegenfuss, Marc
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 302 (17): : 1888 - 1895
  • [3] EPIDEMIOLOGIC PROGRAMS FOR COMPUTERS AND CALCULATORS - USE OF POISSON REGRESSION-MODELS IN ESTIMATING INCIDENCE RATES AND RATIOS
    FROME, EL
    CHECKOWAY, H
    [J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1985, 121 (02) : 309 - 323
  • [4] Critically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada
    Kumar, Anand
    Zarychanski, Ryan
    Pinto, Ruxandra
    Cook, Deborah J.
    Marshall, John
    Lacroix, Jacques
    Stelfox, Tom
    Bagshaw, Sean
    Choong, Karen
    Lamontagne, Francois
    Turgeon, Alexis F.
    Lapinsky, Stephen
    Ahern, Stephane P.
    Smith, Orla
    Siddiqui, Faisal
    Jouvet, Philippe
    Khwaja, Kosar
    McIntyre, Lauralyn
    Menon, Kusum
    Hutchison, Jamie
    Hornstein, David
    Joffe, Ari
    Lauzier, Francois
    Singh, Jeffrey
    Karachi, Tim
    Wiebe, Kim
    Olafson, Kendiss
    Ramsey, Clare
    Sharma, Sat
    Dodek, Peter
    Meade, Maureen
    Hall, Richard
    Fowler, Robert A.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 302 (17): : 1872 - 1879
  • [5] Acute Myocardial Infarction after Laboratory-Confirmed Influenza Infection
    Kwong, Jeffrey C.
    Schwartz, Kevin L.
    Campitelli, Michael A.
    Chung, Hannah
    Crowcroft, Natasha S.
    Karnauchow, Timothy
    Katz, Kevin
    Ko, Dennis T.
    McGeer, Allison J.
    McNally, Dayre
    Richardson, David C.
    Rosella, Laura C.
    Simor, Andrew
    Smieja, Marek
    Zahariadis, George
    Gubbay, Jonathan B.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (04) : 345 - 353
  • [6] Lachin J, 2010, BIOSTATISTICAL METHO, P382
  • [7] Influenza epidemiology-past, present, and future
    Lagace-Wiens, Philippe R. S.
    Rubinstein, Ethan
    Gumel, Abba
    [J]. CRITICAL CARE MEDICINE, 2010, 38 : E1 - E9
  • [8] Extracorporeal membrane oxygenation in adult patients with severe acute respiratory failure
    Lindskov, C.
    Jensen, R. H.
    Sprogoe, P.
    Klaaborg, K. E.
    Kirkegaard, H.
    Severinsen, I. K.
    Lorentsen, A. G.
    Folkersen, L.
    Ilkjaer, S.
    Pedersen, C. M.
    [J]. ACTA ANAESTHESIOLOGICA SCANDINAVICA, 2013, 57 (03) : 303 - 311
  • [9] Adult refractory hypoxemic acute respiratory distress syndrome treated with extracorporeal membrane oxygenation: the role of a regional referral center
    Michaels, Andrew J.
    Hill, Jonathan G.
    Long, William B.
    Young, Brian P.
    Sperley, Bernie P.
    Shanks, Tanya R.
    Morgan, Lori J.
    [J]. AMERICAN JOURNAL OF SURGERY, 2013, 205 (05) : 492 - 498
  • [10] Extracorporeal Membrane Oxygenation for ARDS: National Trends in the United States 2008-2012
    Natt, Bhupinder S.
    Desai, Hem
    Singh, Nirmal
    Poongkunran, Chithra
    Parthasarathy, Sairam
    Bime, Christian
    [J]. RESPIRATORY CARE, 2016, 61 (10) : 1293 - 1298