New advances in gated materials of mesoporous silica for drug controlled release

被引:81
作者
Huang, Ping [1 ]
Lian, Daizheng [2 ,3 ]
Ma, Hualin [2 ,3 ]
Gao, Nansha [1 ]
Zhao, Limin [4 ]
Luan, Ping [5 ]
Zeng, Xiaowei [1 ]
机构
[1] Sun Yat Sen Univ, Sch Pharmaceut Sci Shenzhen, Inst Pharmaceut, Shenzhen 518107, Peoples R China
[2] Southern Univ Sci & Technol, Jinan Univ, Affiliated Hosp 1,Shenzhen Key Lab Kidney Dis, Shenzhen Peoples Hosp,Clin Med Coll 2,Dept Nephro, Shenzhen 518020, Peoples R China
[3] Southern Univ Sci & Technol, Jinan Univ, Affiliated Hosp 1, Shenzhen Peoples Hosp,Clin Med Coll 2,Dept Radiat, Shenzhen 518020, Peoples R China
[4] Guangdong Pharmaceut Univ, Sch Chem & Chem Engn, Guangzhou 510000, Peoples R China
[5] Shenzhen Univ, Hlth Sci Ctr, Shenzhen 518060, Peoples R China
基金
中国国家自然科学基金;
关键词
Mesoporous silica; Gated materials; Surface modification; Drug delivery; Controlled release; CANCER-THERAPY; IN-VITRO; SURFACE-CHEMISTRY; DELIVERY VEHICLES; NANOPARTICLES; PH; PLATFORM; NANOCARRIERS; STRATEGY; CARRIERS;
D O I
10.1016/j.cclet.2021.06.034
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Drug delivery systems (DDS) are used to deliver therapeutic drugs to improve selectivity and reduce side effects. With the development of nanotechnology, many nanocarriers have been developed and applied to drug delivery, including mesoporous silica. Mesoporous silica nanoparticles (MSNs) have attracted a lot of attention for simple synthesis, biocompatibility, high surface area and pore volume. Based on the pore system and surface modification, gated mesoporous silica nanoparticles can be designed to realize on-command drug release, which provides a new approach for selective delivery of antitumor drugs. Herein, this review mainly focuses on the "gate keepers" of mesoporous silica for drug controlled release in nearly few years (2017-2020). We summarize the mechanism of drug controlled release in gated MSNs and different gated materials: inorganic gated materials, organic gated materials, self-gated drug molecules, and biological membranes. The facing challenges and future prospects of gated MSNs are discussed rationally in the end. (C) 2021 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.
引用
收藏
页码:3696 / 3704
页数:9
相关论文
共 122 条
[1]   Metal organic frameworks modified mesoporous silica nanoparticles (MSN): A nano-composite system to inhibit uncontrolled chemotherapeutic drug delivery from Bare-MSN [J].
Adhikari, Chandan ;
Mishra, Anurag ;
Nayak, Debasis ;
Chakraborty, Anjan .
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2018, 47 :1-11
[2]   The In Situ Sulfidation of Cu2O by Endogenous H2S for Colon Cancer Theranostics [J].
An, Lu ;
Wang, Xiaodong ;
Rui, Xichuan ;
Lin, Jiaomin ;
Yang, Hong ;
Tian, Qiwei ;
Tao, Cheng ;
Yang, Shiping .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 57 (48) :15782-15786
[3]   Multifunctional Mesoporous Silica Nanoparticles as a Universal Platform for Drug Delivery [J].
Argyo, Christian ;
Weiss, Veronika ;
Braeuchle, Christoph ;
Bein, Thomas .
CHEMISTRY OF MATERIALS, 2014, 26 (01) :435-451
[4]   Mesoporous Silica Nanoparticles as Theranostic Antitumoral Nanomedicines [J].
Baeza, Alejandro ;
Vallet-Regi, Maria .
PHARMACEUTICS, 2020, 12 (10) :1-16
[5]   Lectin-gated and glycan functionalized mesoporous silica nanocontainers for targeting cancer cells overexpressing Lewis X antigen [J].
Bhat, R. ;
Garcia, I. ;
Aznar, E. ;
Arnaiz, B. ;
Martinez-Bisbal, M. C. ;
Liz-Marzan, L. M. ;
Penades, S. ;
Martinez-Manez, R. .
NANOSCALE, 2018, 10 (01) :239-249
[6]   Carbon dots: Applications in bioimaging and theranostics [J].
Boakye-Yiadom, Kofi Oti ;
Kesse, Samuel ;
Opoku-Damoah, Yaw ;
Filli, Mensura Sied ;
Aquib, Md ;
Joelle, Mily Maviah Bazezy ;
Farooq, Muhammad Asim ;
Mavlyanova, Rukhshona ;
Raza, Faisal ;
Bavi, Rohit ;
Wang, Bo .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2019, 564 :308-317
[7]   Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery: an update [J].
Castillo, Rafael R. ;
Lozano, Daniel ;
Gonzalez, Blanca ;
Manzano, Miguel ;
Izquierdo-Barba, Isabel ;
Vallet-Regi, Maria .
EXPERT OPINION ON DRUG DELIVERY, 2019, 16 (04) :415-439
[8]   Recent applications of the combination of mesoporous silica nanoparticles with nucleic acids: development of bioresponsive devices, carriers and sensors [J].
Castillo, Rafael R. ;
Baeza, Alejandro ;
Vallet-Regi, Maria .
BIOMATERIALS SCIENCE, 2017, 5 (03) :353-377
[9]   Preparation and identification of multifunctional mesoporous silica nanoparticles for in vitro and in vivo dual-mode imaging, theranostics, and targeted tracking [J].
Chan, Ming-Hsien ;
Lin, Hsiu-Mei .
BIOMATERIALS, 2015, 46 :149-158
[10]   Polydopamine-based surface modification of mesoporous silica nanoparticles as pH-sensitive drug delivery vehicles for cancer therapy [J].
Chang, Danfeng ;
Gao, Yongfeng ;
Wang, Lijun ;
Liu, Gan ;
Chen, Yuhan ;
Wang, Teng ;
Tao, Wei ;
Mei, Lin ;
Huang, Laiqiang ;
Zeng, Xiaowei .
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2016, 463 :279-287