Nociceptin/Orphanin FQ Receptor-Driven Heterologous Desensitization of the Major HIV-1 Co-receptor CXCR4

被引：5
作者：
Kaminsky, David E. [2 ]
Rogers, Thomas J. [1 ]
机构：
[1] Temple Univ, Sch Med, Fels Inst Canc Res & Mol Biol, Ctr Inflammat Translat & Clin Lung Res, Philadelphia, PA 19140 USA
[2] Temple Univ, Sch Med, Dept Microbiol & Immunol, Philadelphia, PA 19140 USA
来源：
JOURNAL OF NEUROIMMUNE PHARMACOLOGY | 2011年 / 6卷 / 04期
基金：
美国国家卫生研究院;
关键词：
CHEMOKINE RECEPTORS; HUMAN MONOCYTES; IMMUNE CELLS; EXPRESSION; CCR5; MODULATION; CYTOKINE; SYSTEM;
D O I：
10.1007/s11481-011-9285-4
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
[No abstract available]
引用
收藏
页码：546 / 550
页数：5
相关论文
共 15 条
  • [1] Nociceptin/Orphanin FQ Suppresses Adaptive Immune Responses In Vivo and at Picomolar Levels In Vitro
    Anton, Benito
    Leff, Phillipe
    Meissler, Joseph J.
    Calva, Juan C.
    Acevedo, Rodolfo
    Salazar, Alberto
    Matus, Maura
    Flores, Anabel
    Martinez, Martin
    Adler, Martin W.
    Gaughan, John P.
    Eisenstein, Toby K.
    [J]. JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2010, 5 (01) : 143 - 154
  • [2] Persistent induction of the chemokine receptor CXCR4 by TGF-β1 on synovial T cells contributes to their accumulation within the rheumatoid synovium
    Buckley, CD
    Amft, N
    Bradfield, PF
    Pilling, D
    Ross, E
    Arenzana-Seisdedos, F
    Amara, A
    Curnow, SJ
    Lord, JM
    Scheel-Toellner, D
    Salmon, M
    [J]. JOURNAL OF IMMUNOLOGY, 2000, 165 (06) : 3423 - 3429
  • [3] Opiold and nociceptin receptors regulate cytokine and cytokine receptor expression
    Finley, M. J.
    Happel, C. M.
    Kaminsky, D. E.
    Rogers, T. J.
    [J]. CELLULAR IMMUNOLOGY, 2008, 252 (1-2) : 146 - 154
  • [4] Human neutrophils as a source of nociceptin: A novel link between pain and inflammation
    Fiset, MT
    Gilbert, C
    Poubelle, PE
    Pouliot, M
    [J]. BIOCHEMISTRY, 2003, 42 (35) : 10498 - 10505
  • [5] Orphanin FQ/nociceptin interactions with the immune system in vivo: Gene expression changes in lymphoid organs and regulation of the cytokine response to staphylococcal enterotoxin A
    Goldfarb, Yael
    Reinscheid, Rainer K.
    Kusnecov, Alexander W.
    [J]. JOURNAL OF NEUROIMMUNOLOGY, 2006, 176 (1-2) : 76 - 85
  • [6] Opiates transdeactivate chemokine receptors:: δ and μ opiate receptor-mediated heterologous desensitization
    Grimm, MC
    Ben-Baruch, A
    Taub, DD
    Howard, OMZ
    Resau, JH
    Wang, JM
    Ali, H
    Richardson, R
    Snyderman, R
    Oppenheim, JJ
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1998, 188 (02) : 317 - 325
  • [7] Heterologous desensitization of T cell functions by CCR5 and CXCR4 ligands: inhibition of cellular signaling, adhesion and chemotaxis
    Hecht, I
    Cahalon, L
    Hershkoviz, R
    Lahat, A
    Franitza, S
    Lider, O
    [J]. INTERNATIONAL IMMUNOLOGY, 2003, 15 (01) : 29 - 38
  • [8] Suppression of CCL2/MCP-1 and CCL5/RANTES expression by nociceptin in human monocytes
    Kaminsky, David E.
    Rogers, Thomas J.
    [J]. JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2008, 3 (02) : 75 - 82
  • [9] Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and μ opioid receptors involves protein kinase C:: A molecular mechanism for heterologous cross-talk
    Mandyam, CD
    Thakker, DR
    Christensen, JL
    Standifer, KM
    [J]. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2002, 302 (02) : 502 - 509
  • [10] Regulation of nociceptin/orphaninFQ secretion by immune cells and functional modulation of interleukin-2
    Miller, Thomas R.
    Fulford, Allison J.
    [J]. PEPTIDES, 2007, 28 (11) : 2243 - 2252
12