Clopidogrel hyporesponsiveness and the FDA boxed warning: Detection and management of patients with genetic polymorphisms

被引:7
作者
Perry, Elizabeth [1 ]
机构
[1] Univ Louisiana, Monroe Coll Pharm, Shreveport, LA 71103 USA
关键词
PERCUTANEOUS CORONARY INTERVENTION; PLATELET ACTIVATION; PRASUGREL; THROMBOLYSIS; INHIBITION; COMMON;
D O I
10.2146/ajhp100422
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:529 / 532
页数:4
相关论文
共 21 条
[1]  
[Anonymous], VERIFYNOW P2Y12 TEST
[2]   Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel [J].
Brandt, J. T. ;
Close, S. L. ;
Iturria, S. J. ;
Payne, C. D. ;
Farid, N. A. ;
Ernest, C. S., II ;
Lachno, D. R. ;
Salazar, D. ;
Winters, K. J. .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2007, 5 (12) :2429-2436
[3]   Comparison of Platelet Function Tests in Predicting Clinical Outcome in Patients Undergoing Coronary Stent Implantation [J].
Breet, Nicoline J. ;
van Werkum, Jochem W. ;
Bouman, Heleen J. ;
Kelder, Johannes C. ;
Ruven, Henk J. T. ;
Bal, Egbert T. ;
Deneer, Vera H. ;
Harmsze, Ankie M. ;
van der Heyden, Jan A. S. ;
Rensing, Benno J. W. M. ;
Suttorp, Maarten J. ;
Hackeng, Christian M. ;
ten Berg, Jurrien M. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 303 (08) :754-762
[4]  
*BRIST MYERS SQUIB, 2010, PLAV CLOP PACK INS
[5]   Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study [J].
Collet, Jean-Philippe ;
Hulot, Jean-Sebastien ;
Pena, Anna ;
Villard, Eric ;
Esteve, Jean-Baptiste ;
Silvain, Johanne ;
Payot, Laurent ;
Brugier, Delphine ;
Cayla, Guillaume ;
Beygui, Farzin ;
Bensimon, Gilbert ;
Funck-Brentano, Christian ;
Montalescot, Gilles .
LANCET, 2009, 373 (9660) :309-317
[6]  
Food and Drug Administration, FDA DRUG SAF COMM RE
[7]   Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement [J].
Hochholzer, Willibald ;
Trenk, Dietmar ;
Bestehorn, Hans-Peter ;
Fischer, Benjamin ;
Valina, Christian M. ;
Ferenc, Miroslaw ;
Gick, Michael ;
Caputo, Angelika ;
Buettner, Heinz Joachim ;
Neumann, Franz-Josef .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 48 (09) :1742-1750
[8]  
HUGHES S, GRAVITAS NO BENEFIT
[9]   Cytochrorne P4502C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects [J].
Hulot, Jean-Sebastien ;
Bura, Alessandra ;
Villard, Eric ;
Azizi, Michel ;
Remones, Veronique ;
Goyenvalle, Catherine ;
Aiach, Martine ;
Lechat, Philippe ;
Gaussem, Pascale .
BLOOD, 2006, 108 (07) :2244-2247
[10]   Impact of high loading and maintenance dose of clopidogrel within the first 15 days after percutaneous coronary intervention on patient outcome [J].
Lemesle, Gilles ;
Delhaye, Cedric ;
Sudre, Arnaud ;
Broucqsault, Damien ;
Rosey, Guillaume ;
Bauters, Christophe ;
Lablanche, Jean-Marc .
AMERICAN HEART JOURNAL, 2009, 157 (02) :375-382