Cephalostatin syntheses. 10. An efficient protocol for the synthesis of unsymmetrical pyrazines. Total synthesis of dihydrocephalostatin

被引：47

作者：

Guo, CX

Bhandaru, S

Fuchs, PL

机构：

[1] PURDUE UNIV, DEPT CHEM, W LAFAYETTE, IN 47907 USA

[2] NCI, LAB DRUG DISCOVERY RES & DEV, FREDERICK, MD 21702 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1996年 / 118卷 / 43期

关键词：

D O I：

10.1021/ja962646q

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：10672 / 10673

页数：2

共 18 条

[1] SYNTHESIS OF A C-14',C-15' DIHYDRO DERIVATIVE OF THE SOUTH HEXACYCLIC STEROID UNIT OF CEPHALOSTATIN-1 .1. REGIOSPECIFIC RH[II]-MEDIATED INTERMOLECULAR OXYGEN ALKYLATION OF A PRIMARY NEOPENTYL ALCOHOL [J].

BHANDARU, S ;

FUCHS, PL .

TETRAHEDRON LETTERS, 1995, 36 (46) :8347-8350

[2] SYNTHESIS OF A C-14,C-15 DIHYDRO DERIVATIVE OF THE SOUTH HEXACYCLIC STEROID UNIT OF CEPHALOSTATIN-1 .2. SPIROKETAL SYNTHESIS AND STEREOCHEMICAL ASSIGNMENT BY NMR-SPECTROSCOPY [J].

BHANDARU, S ;

FUCHS, PL .

TETRAHEDRON LETTERS, 1995, 36 (46) :8351-8354

[3]

Boyd M. R., 1993, CURRENT THERAPY ONCO, P11

[4] SOME PRACTICAL CONSIDERATIONS AND APPLICATIONS OF THE NATIONAL-CANCER-INSTITUTE IN-VITRO ANTICANCER DRUG DISCOVERY SCREEN [J].

BOYD, MR ;

PAULI, KD .

DRUG DEVELOPMENT RESEARCH, 1995, 34 (02) :91-109

[5] 10 MORE RITTERAZINES, CYTOTOXIC STEROIDAL ALKALOIDS FROM THE TUNICATE RITTERELLA-TOKIOKA [J].

FUKUZAWA, S ;

MATSUNAGA, S ;

FUSETANI, N .

TETRAHEDRON, 1995, 51 (24) :6707-6716

[6] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF UNSYMMETRICAL BIS-STEROIDAL PYRAZINES RELATED TO THE CYTOTOXIC MARINE NATURAL PRODUCT CEPHALOSTATIN-1 [J].

HEATHCOCK, CH ;

SMITH, SC .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (22) :6828-6839

[7]

JOENG JU, 1995, J AM CHEM SOC, V117, P10157

[8] A SHORT ROUTE TO CEPHALOSTATIN ANALOGS [J].

KRAMER, A ;

ULLMANN, U ;

WINTERFELDT, E .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1993, (23) :2865-2867

[9] SYNTHESIS OF EUPOLAURAMINE VIA AN INTRAMOLECULAR KONDRATEVA PYRIDINE SYNTHESIS [J].

LEVIN, JI ;

WEINREB, SM .

JOURNAL OF ORGANIC CHEMISTRY, 1984, 49 (23) :4325-4332

[10] THE USE OF TETRAMETHYLGUANIDINIUM AZIDE IN NONHALOGENATED SOLVENTS AVOIDS POTENTIAL EXPLOSION HAZARDS [J].

LI, C ;

SHIH, TL ;

JEONG, JU ;

ARASAPPAN, A ;

FUCHS, PL .

TETRAHEDRON LETTERS, 1994, 35 (17) :2645-2646

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