Double Chirality Transmission in Trityl Amines: Sensing Molecular Dynamic Stereochemistry by Circular Dichroism and DFT Calculations

被引：38

作者：

Sciebura, Jacek ^{[1
]}

Gawronski, Jacek ^{[1
]}

机构：

[1] Adam Mickiewicz Univ Poznan, Dept Chem, PL-60780 Poznan, Poland

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2011年 / 17卷 / 47期

关键词：

amine configuration; chirality; circular dichroism; density functional calculations; trityl amines; X-RAY STRUCTURE; CONFORMATIONAL-ANALYSIS; ABSOLUTE-CONFIGURATION; NITROGEN ATOM; HELICITY; ALCOHOLS; SPECTRA; BASE;

D O I：

10.1002/chem.201101699

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Con-figured out: The tert-butyl group can be formally seen as "less" sterically demanding (M) than the methyl group (L). This is the case when a CD-active trityl group at the nitrogen atom is used to report the chirality of the carbon substituent with two different sized groups (see scheme). The use of the trityl CD sensor allowed, in addition, the determination of the dominant absolute configuration of the nitrogen atom in chiral amines. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：13138 / 13141

页数：4

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[2] Diffuse reflectance circular dichroism for the detection of molecular chirality: An application in remote sensing of flora
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[3] Dynamic Molecular Propeller: Supramolecular Chirality Sensing by Enhanced Chiroptical Response through the Transmission of Point Chirality to Mobile Helicity
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CHEMPHYSCHEM, 2018, 19 (18) : 2321 - 2330
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