The role of low-molecular-weight heparin in recurrent implantation failure: a prospective, quasi-randomized, controlled study

被引:48
作者
Berker, Bulent [1 ]
Taskin, Salih [1 ]
Kahraman, Korhan [1 ]
Taskin, Elif Aylin [1 ]
Atabekoglu, Cem [1 ]
Sonmezer, Murat [1 ]
机构
[1] Ankara Univ, Tip Fak, Kadin Hastaliklari & Dogum Anabilim Dali, Sch Med, TR-06100 Ankara, Turkey
关键词
Recurrent implantation failure; low molecular weight heparin; pregnancy outcome; implantation; EPIDERMAL-GROWTH-FACTOR; VITRO TROPHOBLAST INVASIVENESS; CELLS IN-VITRO; HUMAN BLASTOCYST; E-CADHERIN; BINDING; EGF; EXPRESSION; PREGNANCY; SURVIVAL;
D O I
10.1016/j.fertnstert.2010.12.033
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Low-molecular-weight heparin did not provide any beneficial effect on pregnancy outcomes in patients with two or more implantation failures. Further trials are needed to confirm a trend in favor of low-molecular-weight heparin in the subgroup with women with three or more implantation failures. (Fertil Steril (R) 2011; 95: 2499-502. (c) 2011 by American Society for Reproductive Medicine.)
引用
收藏
页码:2499 / 2502
页数:4
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