Two-Photon Fluorescent Probes for Metal Ions

被引：128

作者：

Kim, Hwan Myung ^{[1
]}

Cho, Bong Rae ^{[2
]}

机构：

[1] Ajou Univ, Div Energy Syst Res, Suwon 443749, South Korea

[2] Korea Univ, Dept Chem, Res Inst Nat Sci, Seoul 136701, South Korea

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2011年 / 6卷 / 01期

关键词：

fluorescent probes; in vivo imaging; metal ions; nonlinear spectroscopy; two-photon microscopy; MEMBRANE CALCIUM-IONS; ABSORBING MATERIALS; ZINC; ABSORPTION; CA2+; MAGNESIUM; MERCURY; DESIGN; SENSOR; CELLS;

D O I：

10.1002/asia.201000542

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two-photon microscopy (TPM) has become an indispensible tool in biology and medicine owing to the capability of imaging the intact tissue for a long period of time. To make it a versatile tool in biology, a variety of two-photon probes for specific applications are needed. In this context, many research groups are developing two-photon probes for various applications. In this Focus Review, we summarize recent results on model studies and selected examples of two-photon probes that can detect intracellular free metal ions in live cells and tissues to provide a guideline for the design of useful two-photon probes for various in vivo imaging applications.

引用

页码：58 / 69

页数：12