Two-Photon Fluorescent Probes for Metal Ions

被引：128
作者：
Kim, Hwan Myung [1 ]
Cho, Bong Rae [2 ]
机构：
[1] Ajou Univ, Div Energy Syst Res, Suwon 443749, South Korea
[2] Korea Univ, Dept Chem, Res Inst Nat Sci, Seoul 136701, South Korea
来源：
CHEMISTRY-AN ASIAN JOURNAL | 2011年 / 6卷 / 01期
关键词：
fluorescent probes; in vivo imaging; metal ions; nonlinear spectroscopy; two-photon microscopy; MEMBRANE CALCIUM-IONS; ABSORBING MATERIALS; ZINC; ABSORPTION; CA2+; MAGNESIUM; MERCURY; DESIGN; SENSOR; CELLS;
D O I：
10.1002/asia.201000542
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Two-photon microscopy (TPM) has become an indispensible tool in biology and medicine owing to the capability of imaging the intact tissue for a long period of time. To make it a versatile tool in biology, a variety of two-photon probes for specific applications are needed. In this context, many research groups are developing two-photon probes for various applications. In this Focus Review, we summarize recent results on model studies and selected examples of two-photon probes that can detect intracellular free metal ions in live cells and tissues to provide a guideline for the design of useful two-photon probes for various in vivo imaging applications.
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收藏
页码：58 / 69
页数：12
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