Treatment of Severe Hypervolemic Hyponatremia in a Child With Pneumonia

被引：3

作者：

Genoni, Teresa ^{[1
,2
]}

Tenconi, Rossana ^{[1
,2
]}

Bertolozzi, Giuseppe ^{[1
,2
]}

Laicini, Emanuela Anna ^{[1
,2
]}

Tardini, Giacomo ^{[1
,2
]}

Vianello, Federica ^{[1
,2
]}

Leva, Ernesto ^{[3
]}

Milani, Gregorio Paolo ^{[1
,2
]}

Fossali, Emilio Filippo ^{[1
,2
]}

机构：

[1] Univ Milan, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dept Pediat Emergency, Via Commenda 9, I-20122 Milan, Italy

[2] Univ Milan, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dept Pathophysiol & Transplantat, I-20122 Milan, Italy

[3] Univ Milan, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dept Pediat Surg, I-20122 Milan, Italy

来源：

PEDIATRIC EMERGENCY CARE | 2016年 / 32卷 / 06期

关键词：

hyponatremia; intravenous fluids; diuretics; INAPPROPRIATE SECRETION; ANTIDIURETIC-HORMONE; PEDIATRIC-PATIENT; CONIVAPTAN; BRAIN;

D O I：

10.1097/PEC.0000000000000823

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A 21-month-old boy came to our attention because of pneumonia. His weight increased before presentation, and his blood test results showed hyponatremia (116 mEq/L), low plasma osmolarity (241 mOsm/L), and high urine osmolarity (435 mOsm/L). He was treated with 0.9% sodium chloride solution and intravenous furosemide, and sodium levels rose up to 135 mEq/L in 36 hours. No standard treatment is available for severe hyponatremia in children. The use of vaptans in pediatric patients is described in literature, but it lacks evidence about safety and effectiveness. We suggest that furosemide administration plus salt replacement is effective in restoring normal values of plasma sodium concentration in severe euvolemic and hypervolemic hyponatremia.

引用

页码：390 / 391

页数：2

共 12 条

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