Human Cardiac Tissue Collagen Polarity Revealed Using Polarimetric Second-Harmonic Generation Microscopy

被引：0

作者：

Mirsanaye, Kamdin ^{[1
,2
]}

Golaraei, Ahmad ^{[1
,2
,3
]}

Habach, Fayez ^{[1
,2
]}

Zurauskas, Edvardas ^{[4
]}

Venius, Jonas ^{[5
,6
]}

Rotomskis, Ricardas ^{[5
,7
]}

Barzda, Virginijus ^{[1
,2
,7
]}

机构：

[1] Univ Toronto, Dept Phys, Toronto, ON, Canada

[2] Univ Toronto, Dept Chem & Phys Sci, Toronto, ON, Canada

[3] Univ Hlth Network, Princess Margaret Canc Ctr, Toronto, ON, Canada

[4] Vilnius Univ Hosp, Natl Ctr Pathol, Vilnius, Lithuania

[5] Natl Canc Inst, Biomed Phys Lab, Vilnius, Lithuania

[6] Natl Canc Inst, Dept Med Phys, Vilnius, Lithuania

[7] Vilnius Univ, Laser Res Ctr, Vilnius, Lithuania

来源：

2019 PHOTONICS NORTH (PN) | 2019年

基金：

加拿大健康研究院; 加拿大自然科学与工程研究理事会;

关键词：

Nonlinear Microscopy; Polarimetry; Collagen; Second-Harmonic Generation; Cardiac Tissue;

D O I：

10.1109/pn.2019.8819536

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Polarimetric second-harmonic generation microscopy is a label-free imaging technique, which enables detailed ultrastructural investigations of the biomaterials. The structural information is extracted in the form of achiral and chiral nonlinear susceptibility element ratios, which aid in characterization of subtle variations in the composition and organization of collagen.

引用

页数：1