A new phenylpropanoid from the roots of Euphorbia nematocypha

被引：12

作者：

Jia, Hai-Yang ^{[1
,2
]}

Liao, Zhi-Xin ^{[1
,2
]}

Liu, Fu-Yue ^{[1
]}

Wu, Ling ^{[1
]}

Xu, Chen ^{[1
]}

Zuo, Bo ^{[1
]}

机构：

[1] Southeast Univ, Sch Chem & Chem Engn, Dept Pharmaceut Engn, Nanjing 211189, Jiangsu, Peoples R China

[2] Southeast Univ, Jiang Su Prov Hitech Key Lab Biomed Res, Nanjing 211189, Jiangsu, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2015年 / 29卷 / 07期

关键词：

eunicellan antiproliferative; Euphorbia nematocypha; 16-O-caffeoyl-16-hydroxylhexadecanoic acid; phenylpropanoid; BIOLOGICAL-ACTIVITY; DITERPENOIDS; CHEMISTRY; JOLKINI; PLANTS;

D O I：

10.1080/14786419.2014.980256

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A phytochemical investigation of the ethanolic extracts of the dried roots of Euphorbia nematocypha resulted in the isolation of a new phenylpropanoid, 16-O-caffeoyl-16-hydroxylhexadecanoic acid (1), together with 23 known compounds (2-24). Their structures were elucidated on the basis of spectroscopic data. Compound 1 was first to be isolated as a caffeic acyl long chain alkyl acid from the family Euphorbiaceae. The new isolated phenylpropanoid showed potent cytotoxic activities against the MCF-7 and HeLa cell lines.

引用

页码：650 / 655

页数：6

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