Decreases in Hepatitis C Testing and Treatment During the COVID-19 Pandemic

被引：64

作者：

Kaufman, Harvey W. ^{[1
]}

Bull-Otterson, Lara ^{[2
]}

Meyer, William A., III ^{[1
]}

Huang, Xiaohua ^{[1
]}

Doshani, Mona ^{[3
]}

Thompson, William W. ^{[3
]}

Osinubi, Ademola ^{[3
]}

Khan, Mohammed A. ^{[3
]}

Harris, Aaron M. ^{[3
]}

Gupta, Neil ^{[3
]}

Van Handel, Michelle ^{[3
]}

Wester, Carolyn ^{[3
]}

Mermin, Jonathan ^{[3
]}

Nelson, Noele P. ^{[3
]}

机构：

[1] Quest Diagnost, Secaucus, NJ USA

[2] US Ctr Dis Control & Prevent, Div Hlth Informat & Surveillance, Ctr Surveillance Epidemiol, Atlanta, GA USA

[3] US Ctr Dis Control & Prevent, Lab Serv, Atlanta, GA USA

来源：

AMERICAN JOURNAL OF PREVENTIVE MEDICINE | 2021年 / 61卷 / 03期

关键词：

UNITED-STATES; VIRUS-INFECTION; CARE; HCV; LINKAGE; RECOMMENDATIONS; INTERVENTIONS; DISPARITIES; PEOPLE; ADULTS;

D O I：

10.1016/j.amepre.2021.03.011

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Introduction: The COVID-19 pandemic has disrupted healthcare services, reducing opportunities to conduct routine hepatitis C virus antibody screening, clinical care, and treatment. Therefore, people living with undiagnosed hepatitis C virus during the pandemic may later become identified at more advanced stages of the disease, leading to higher morbidity and mortality rates. Further, unidentified hepatitis C virus-infected individuals may continue to unknowingly transmit the virus to others. Methods: To assess the impact of the COVID-19 pandemic, data were evaluated from a large national reference clinical laboratory and from national estimates of dispensed prescriptions for hepatitis C virus treatment. Investigators estimated the average number of hepatitis C virus antibody tests, hepatitis C virus antibody-positive test results, and hepatitis C virus RNA-positive test results by month in January-July for 2018 and 2019, compared with the same months in 2020. To assess the impact of hepatitis C virus treatment, dispensed hepatitis C virus direct-acting antiretroviral medications were examined for the same time periods. Statistical analyses of trends were performed using negative binomial models. Results: Compared with the 2018 and 2019 months, hepatitis C virus antibody testing volume decreased 59% during April 2020 and rebounded to a 6% reduction in July 2020. The number of hepatitis C virus RNA-positive results fell by 62% in March 2020 and remained 39% below the baseline by July 2020. For hepatitis C virus treatment, prescriptions decreased 43% in May, 37% in June, and 38% in July relative to the corresponding months in 2018 and 2019. Conclusions: During the COVID-19 pandemic, continued public health messaging, interventions and outreach programs to restore hepatitis C virus testing and treatment to prepandemic levels, and maintenance of public health efforts to eliminate hepatitis C infections remain important. (C) 2021 American Journal of Preventive Medicine. Published by Elsevier Inc.

引用

页码：369 / 376

页数：8

共 37 条

[31]

Smith Bryce D., 2012, Morbidity and Mortality Weekly Report, V61, P1

[32] Impact of the 2020 COVID-19 Pandemic on Ambulatory Hepatitis C Testing [J].

Sperring, Heather ;

Ruiz-Mercado, Glorimar ;

Schechter-Perkins, Elissa M. .

JOURNAL OF PRIMARY CARE AND COMMUNITY HEALTH, 2020, 11

[33] Low Uptake of Direct-acting Antiviral Therapy Among Hepatitis C Patients With Advanced Liver Disease and Access to Care, 2014-2017 [J].

Spradling, Philip R. ;

Xing, Jian ;

Rupp, Loralee B. ;

Moorman, Anne C. ;

Gordon, Stuart C. ;

Lu, Mei ;

Teshale, Eyasu H. ;

Boscarino, Joseph A. ;

Schmidt, Mark A. ;

Daida, Yihe G. ;

Holmberg, Scott D. .

JOURNAL OF CLINICAL GASTROENTEROLOGY, 2021, 55 (01) :77-83

[34]

Stephenson J, JAMA HLTH FORUM, DOI [10.1001/jamahealthforum.2020.0685, DOI 10.1001/JAMAHEALTHFORUM.2020.0685]

[35] Screening for Hepatitis C Virus Infection in Adolescents and Adults US Preventive Services Task Force Recommendation Statement [J].

Owens D.K. ;

Davidson K.W. ;

Krist A.H. ;

Barry M.J. ;

Cabana M. ;

Caughey A.B. ;

Donahue K. ;

Doubeni C.A. ;

Epling J.W. ;

Kubik M. ;

Ogedegbe G. ;

Pbert L. ;

Silverstein M. ;

Simon M.A. ;

Tseng C.-W. ;

Wong J.B. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (10) :970-975

[36]

Valdiserri R, 2020, USES ADVERSITY LEVER, DOI [10.1377/hblog20200624.84875/full/, DOI 10.1377/HBLOG20200624.84875/FULL]

[37] COVID-19 and Racial/Ethnic Disparities [J].

Webb Hooper, Monica ;

Napoles, Anna Maria ;

Perez-Stable, Eliseo J. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (24) :2466-2467

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