Notoamide O, a Structurally Unprecedented Prenylated Indole Alkaloid, and Notoamides P-R from a Marine-Derived Fungus, Aspergillus sp.

被引：101

作者：

Tsukamoto, Sachiko ^{[1
,2
]}

Umaoka, Hideharu ^{[1
]}

Yoshikawa, Kohei ^{[2
]}

Ikeda, Tsuyoshi ^{[1
]}

Hirota, Hiroshi ^{[3
]}

机构：

[1] Kumamoto Univ, Grad Sch Pharmaceut Sci, Kumamoto 8620973, Japan

[2] Chiba Univ, Grad Sch Sci, Inage Ku, Chiba 2638522, Japan

[3] RIKEN, GSC, Tsurumi Ku, Yokohama, Kanagawa 2300045, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2010年 / 73卷 / 08期

关键词：

BIOMIMETIC TOTAL-SYNTHESIS; (-)-VERSICOLAMIDE B; STEPHACIDIN-A; CONCISE; MALBRANCHEAMIDE; METABOLITES;

D O I：

10.1021/np1002498

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Notoamides O-R were isolated from a marine-derived Aspergillus sp. Notoamide O possesses a novel hemiacetal/hemiaminal ether functionality hitherto unknown among this family of prenylated indole alkaloids. The structure represents an unusual branch point for the oxidative modification of other members in the family of prenylated indole alkaloids in the biogenetic pathway.

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收藏

页码：1438 / 1440

页数：3

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