Role of cardiac power in heart failure

被引:126
|
作者
Cotter, G [1 ]
Williams, SG
Vered, Z
Tan, LB
机构
[1] Assaf Harofeh Med Ctr, Dept Cardiol, Cardiol Inst, IL-70300 Zerifin, Israel
[2] Univ Leeds, Gen Infirm, Unit Mol Vasc Med, Leeds LS1 3EX, W Yorkshire, England
关键词
heart failure; cardiac power output; hemodynamics; cardiac reserve; cardiac function;
D O I
10.1097/00001573-200305000-00007
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The heart is a muscular mechanical pump with an ability to generate both flow (cardiac output) and pressure. The product of flow output and systemic arterial pressure is the rate of useful work done, or power output. Cardiac pumping capability can be defined as the cardiac power output (CPOmax) achieved by the heart during maximal stimulation. Cardiac reserve is the increase in power output as the cardiac performance is increased from the resting to the maximally stimulated state. Recently, several studies have shown that CPOmax, a direct indicator of overall cardiac function, measured directly or as an approximation, is a major determinant of exercise capacity and a most powerful predictor of prognosis for patients with chronic heart failure. The same holds true in acute heart failure, where it is also useful in subclassifying the conditions to select the appropriate treatment.
引用
收藏
页码:215 / 222
页数:8
相关论文
共 50 条
  • [41] Cardiac mitochondrial energy metabolism in heart failure: Role of cardiolipin and sirtuins
    Dolinsky, Vernon W.
    Cole, Laura K.
    Sparagna, Genevieve C.
    Hatch, Grant M.
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2016, 1861 (10): : 1544 - 1554
  • [42] Role of micro RNAs in cardiac hypertrophy, myocardial fibrosis and heart failure
    Dong, De-li
    Yang, Bao-feng
    ACTA PHARMACEUTICA SINICA B, 2011, 1 (01) : 1 - 7
  • [43] Immunity, Inflammation and Heart Failure: Their Role on Cardiac Function and Iron Status
    Perticone, Maria
    Zito, Roberta
    Miceli, Sofia
    Pinto, Angelina
    Suraci, Edoardo
    Greco, Marta
    Gigliotti, Simona
    Hribal, Marta Letizia
    Corrao, Salvatore
    Sesti, Giorgio
    Perticone, Francesco
    FRONTIERS IN IMMUNOLOGY, 2019, 10
  • [44] Cardiac Remodeling in Heart Failure: Role of Pyroptosis and Its Therapeutic Implications
    Chai, Ruoning
    Xue, Wenjing
    Shi, Shuqing
    Zhou, Yu
    Du, Yihang
    Li, Yuan
    Song, Qingqiao
    Wu, Huaqin
    Hu, Yuanhui
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, 9
  • [45] Risk stratification in acute decompensated heart failure: the role of cardiac troponin
    Mueller, Christian
    NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE, 2008, 5 (11): : 680 - 681
  • [46] SUDDEN CARDIAC DEATH IN HEART-FAILURE - THE ROLE OF ABNORMAL REPOLARIZATION
    TOMASELLI, GF
    BEUCKELMANN, DJ
    CALKINS, HG
    BERGER, RD
    KESSLER, PD
    LAWRENCE, JH
    KASS, D
    FELDMAN, AM
    MARBAN, E
    CIRCULATION, 1994, 90 (05) : 2534 - 2539
  • [47] The role of pharmacotherapy in the prevention of sudden cardiac death in patients with heart failure
    Phillip A. Weeks
    Adam Sieg
    Jennifer Ann Gass
    Indranee Rajapreyar
    Heart Failure Reviews, 2016, 21 : 415 - 431
  • [48] Emerging role of liver X receptors in cardiac pathophysiology and heart failure
    Megan V. Cannon
    Wiek H. van Gilst
    Rudolf A. de Boer
    Basic Research in Cardiology, 2016, 111
  • [49] The potential role of cardiac resynchronization therapy in acute heart failure syndromes
    Wang, Norman C.
    Bhattacharya, Sanjoy
    Gheorghiade, Mihai
    HEART FAILURE REVIEWS, 2011, 16 (05) : 481 - 490
  • [50] The Role of Thyroid Hormones in Heart Failure
    Vale, Catarina
    Neves, Joao Sergio
    von Hafe, Madalena
    Borges-Canha, Marta
    Leite-Moreira, Adelino
    CARDIOVASCULAR DRUGS AND THERAPY, 2019, 33 (02) : 179 - 188