Update on subclinical thyroid dysfunction

被引:11
作者
Hashimoto, Koshi [1 ]
机构
[1] Dokkyo Med Univ, Saitama Med Ctr, Dept Diabet Endocrinol & Hematol, 2-1-50 Minami Koshigaya, Saitama 3438555, Japan
关键词
Subclinical hypothyroidism (SCH); Subclinical hyperthyroidism (SCHyper); TSH harmonization; CORONARY-HEART-DISEASE; ALL-CAUSE MORTALITY; CLINICAL-PRACTICE GUIDELINES; 5-YEAR FOLLOW-UP; RISK-FACTORS; CARDIOVASCULAR RISK; AMERICAN ASSOCIATION; LEVOTHYROXINE REPLACEMENT; MYOCARDIAL-INFARCTION; NATURAL-HISTORY;
D O I
10.1507/endocrj.EJ22-0182
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Subclinical thyroid dysfunction is defined by serum thyroid-stimulating hormone (TSH) levels either greater or less than the reference range with normal thyroxine (T4) concentrations, and consists of subclinical hypothyroidism (SCH) and subclinical hyperthyroidism (SCHyper). For the proper diagnosis of SCH, it is most important to be able to correctly evaluate the serum TSH levels, which have numerous unique characteristics. We also need to be versed in TSH harmonization, which was recently launched world-wide. In this review, we will attempt to determine the best clinical approaches to the treatment of subclinical thyroid dysfunction based on recent guidelines published from several countries and novel findings of several recent large-scale clinical studies.
引用
收藏
页码:725 / 738
页数:14
相关论文
共 118 条
  • [1] The spectrum of thyroid disorders in an iodine-deficient community: The Pescopagano survey
    Aghini-Lombardi, F
    Antonangeli, L
    Martino, E
    Vitti, P
    Maccherini, D
    Leoli, F
    Rago, T
    Grasso, L
    Valeriano, R
    Balestrieri, A
    Pinchera, A
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (02) : 561 - 566
  • [2] 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum
    Alexander, Erik K.
    Pearce, Elizabeth N.
    Brent, Gregory A.
    Brown, Rosalind S.
    Chen, Herbert
    Dosiou, Chrysoula
    Grobman, William A.
    Laurberg, Peter
    Lazarus, John H.
    Mandel, Susan J.
    Peeters, Robin P.
    Sullivan, Scott
    [J]. THYROID, 2017, 27 (03) : 315 - +
  • [3] Levothyroxine Substitution in Patients with Subclinical Hypothyroidism and the Risk of Myocardial Infarction and Mortality
    Andersen, Mette Nygaard
    Olsen, Anne-Marie Schjerning
    Madsen, Jesper Clausager
    Faber, Jens
    Torp-Pedersen, Christian
    Gislason, Gunnar Hilmar
    Selmer, Christian
    [J]. PLOS ONE, 2015, 10 (06):
  • [4] Thyrotropin levels and risk of fatal coronary heart disease
    Asvold, Bjorn O.
    Bjoro, Trine
    Nilsen, Tom Ivar L.
    Gunnell, David
    Vatten, Lars J.
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2008, 168 (08) : 855 - 860
  • [5] The association between TSH within the reference range and serum lipid concentrations in a population-based study.: The HUNT Study (vol 156, pg 181, 2007)
    Asvold, Bjorn O.
    Vatten, Lars J.
    Nilsen, Tom I. L.
    Bjoro, Trine
    [J]. EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2007, 156 (06) : 707 - 707
  • [6] Thyroid function and the risk of coronary heart disease: 12-year follow-up of the HUNT Study in Norway
    Asvold, Bjorn O.
    Bjoro, Trine
    Platou, Carl
    Vatten, Lars J.
    [J]. CLINICAL ENDOCRINOLOGY, 2012, 77 (06) : 911 - 917
  • [7] The association between subclinical thyroid dysfunction and dementia: The Health, Aging and Body Composition (Health ABC) Study
    Aubert, Carole E.
    Bauer, Douglas C.
    da Costa, Bruno R.
    Feller, Martin
    Rieben, Carole
    Simonsick, Eleanor M.
    Yaffe, Kristine
    Rodondi, Nicolas
    [J]. CLINICAL ENDOCRINOLOGY, 2017, 87 (05) : 617 - 626
  • [8] Hyperthyroidism and Other Causes of Thyrotoxicosis: Management Guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists
    Bahn, Rebecca S.
    Burch, Henry B.
    Cooper, David S.
    Garber, Jeffrey R.
    Greenlee, M. Carol
    Klein, Irwin
    Laurberg, Peter
    McDougall, I. Ross
    Montori, Victor M.
    Rivkees, Scott A.
    Ross, Douglas S.
    Sosa, Julie Ann
    Stan, Marius N.
    [J]. THYROID, 2011, 21 (06) : 593 - 646
  • [9] Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline
    Bekkering, G. E.
    Agoritsas, T.
    Lytvyn, L.
    Heen, A. F.
    Feller, M.
    Moutzouri, E.
    Abdulazeem, H.
    Aertgeerts, B.
    Beecher, D.
    Brito, J. P.
    Farhoumand, P. D.
    Ospina, N. Singh
    Rodondi, N.
    van Driel, M.
    Wallace, E.
    Snel, M.
    Okwen, P. M.
    Siemieniuk, R.
    Vandvik, P. O.
    Kuijpers, T.
    Vermandere, M.
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2019, 365
  • [10] Subclinical hyperthyroidism and dementia: the Sao Paulo Ageing & Health Study (SPAH)
    Bensenor, Isabela M.
    Lotufo, Paulo A.
    Menezes, Paulo R.
    Scazufca, Marcia
    [J]. BMC PUBLIC HEALTH, 2010, 10