Synthesis and characterization of chitosan and silver loaded chitosan nanoparticles for bioactive polyester

被引：330

作者：

Ali, S. Wazed ^{[1
]}

Rajendran, S. ^{[2
]}

Joshi, Mangala ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Text Technol, New Delhi 110016, Hauz Khas, India

[2] Univ Bolton, Inst Mat Res & Innovat, Bolton BL3 5AB, England

来源：

CARBOHYDRATE POLYMERS | 2011年 / 83卷 / 02期

关键词：

Chitosan nanoparticles; Silver loaded chitosan nanoparticles; TEM; MIC; Polyester; Bioactivity; FINISHES; FIBERS; AGENTS; COTTON;

D O I：

10.1016/j.carbpol.2010.08.004

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The paper focuses on the synthesis of chitosan nanoparticles (CSN) by ionic gelation with sodium tripolyphosphate and subsequently its loading with silver ions to produce silver loaded chitosan nanoparticles (Ag-CSN) The aim was to enhance the antibacterial property of chitosan in the nanoparticle form and thus improve its bactericidal efficacy when applied on polyester fabrics The average particle size of CSN and Ag-CSN was 115 nm and 165 nm respectively The structure of CSN and Ag-CSN was studied by XRD FTIR DSC TGA and TEM analysis The minimum inhibitory concentration of both the CSN and Ag-CSN against Staphylococcus aureus bacteria was found to be 50 and 500 times less respectively as compared to bulk chitosan Silver loading on the synthesized CSN showed synergistic antimicrobial effect against S aureus bacteria The release of Ag+ from Ag-CSN finished polyester fabric is substantiated by antibacterial testing which shows a clear zone of inhibition (C) 2010 Elsevier Ltd All rights reserved

引用

页码：438 / 446

页数：9

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