Follicular acantholysis: A subtle clue to the early diagnosis of pemphigus vulgaris

被引：13

作者：

Mahalingam, M ^{[1
]}

机构：

[1] Quest Diagnost Inc, Cambridge, MA 02139 USA

来源：

AMERICAN JOURNAL OF DERMATOPATHOLOGY | 2005年 / 27卷 / 03期

关键词：

follicular acantholysis; pemphigus vulgaris;

D O I：

10.1097/01.dad.0000138656.86095.f4

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The histologic hallmark of fully established pemphigus vulgaris (PV), a chronic autoimmune disease of the skin and mucosa, is the presence of acantholysis induced at the suprabasal level. This case report of acantholysis restricted to the follicular epithelium as a subtle histologic manifestation of the disease, draws attention to the pitfalls encountered in the histologic diagnosis of early cases of pemphigus vulgaris.

引用

页码：237 / 239

页数：3

共 17 条

[1] ACKERMAN AB, 1978, HISTOLOGIC DIAGNOSIS, P525
[2] ACKERMAN AB, 1997, HISTOLOGIC DIAGNOSIS, P599
[3] AUSPITZ H, 1881, SYSTEM HAUTKRANKHEIT, P143
[4] HAILEY-HAILEY DISEASE - A WIDESPREAD ABNORMALITY OF CELL-ADHESION
BURGE, SM
MILLARD, PR
WOJNAROWSKA, F
[J]. BRITISH JOURNAL OF DERMATOLOGY, 1991, 124 (04) : 329 - 332
[5] Civatte A., 1943, ANN DERM SYPH PARIS, V3, P1
[6] EOSINOPHILIC SPONGIOSIS IN PEMPHIGUS - A REPORT OF AN UNUSUAL HISTOLOGICAL CHANGE IN PEMPHIGUS
EMMERSON, RW
WILSONJO.E
[J]. ARCHIVES OF DERMATOLOGY, 1968, 97 (03) : 252 - +
[7] Pemphigus vulgaris: the other half of the story
Kalish, RS
[J]. JOURNAL OF CLINICAL INVESTIGATION, 2000, 106 (12) : 1433 - 1435
[8] PEMPHIGUS-VULGARIS ANTIGEN IS A DESMOSOMAL DESMOGLEIN
KARPATI, S
AMAGAI, M
PRUSSICK, R
STANLEY, JR
[J]. DERMATOLOGY, 1994, 189 : 24 - 26
[9] Koch PJ, 1998, J CELL SCI, V111, P2529
[10] Histopathologic findings in drug-induced pemphigus
Landau, M
Brenner, S
[J]. AMERICAN JOURNAL OF DERMATOPATHOLOGY, 1997, 19 (04) : 411 - 414

← 1 2 →