Evaluation of electrical characteristics of biological tissue with electrical impedance spectroscopy

被引：33

作者：

Yao, Jiafeng ^{[1
]}

Wang, Li ^{[1
]}

Liu, Kai ^{[1
]}

Wu, Hongtao ^{[1
]}

Wang, Hao ^{[2
]}

Huang, Jingshi ^{[3
]}

Li, Jianping ^{[4
]}

机构：

[1] Nanjing Univ Aeronaut & Astronaut, Coll Mech & Elect Engn, Nanjing, Peoples R China

[2] Guangzhou 12 Hosp, Inst Otolaryngol, Guangzhou, Peoples R China

[3] Shanghai Univ Engn Sci, Sino Korean Sch Multimedia Design, Human LAB, Shanghai, Peoples R China

[4] Zhejiang Normal Univ, Coll Engn, Jinhua, Zhejiang, Peoples R China

来源：

ELECTROPHORESIS | 2020年 / 41卷 / 16-17期

基金：

中国国家自然科学基金;

关键词：

Biomedical measurement; Electrical impedance spectroscopy; Equivalent circuit fitting; Least squares method; THYROID-NODULES; SURGERY;

D O I：

10.1002/elps.201900420

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The electrical characteristics of biological tissue is evaluated by establishing an electrical equivalent circuit with electrical impedance spectroscopy. The least squares method is used to realize electrical equivalent circuit fitting by using the developed portable electrical impedance spectroscopy system. The EIS system is used to obtain the impedance spectrum data of the measured biological tissue. In the experiment, the impedance spectrum data of eggs under different heating time were measured, and the established equivalent circuit model of eggs was fitted by nonlinear least squares fitting algorithm. Moreover, the electrical characteristics of the biological tissue are also revealed by numerical simulation with HANAI model. The experimental and simulation results show that the extracted equivalent electrical parameters can clearly characterize the variation of the internal change of components of biological tissues.

引用

页码：1425 / 1432

页数：8

共 30 条

[1] A clinical study of the use of impedance spectroscopy in the detection of cervical intraepithelial neoplasia (CIN) [J].

Abdul, S ;

Brown, BH ;

Milnes, P ;

Tidy, JA .

GYNECOLOGIC ONCOLOGY, 2005, 99 (03) :S64-S66

[2]

[Anonymous], PARTICULATE SCI TECH

[3]

[Anonymous], IEEE T IND INF

[4] Electrical Impedance Spectroscopy to Aid Parathyroid Identification and Preservation in Central Compartment Neck Surgery: A Proof of Concept in a Rabbit Model [J].

Antakia, Ramez ;

Brown, Brian H. ;

Highfield, Peter E. ;

Stephenson, Tim J. ;

Brown, Nicola J. ;

Balasubramanian, Sabapathy P. .

SURGICAL INNOVATION, 2016, 23 (02) :176-182

[5] Electrical Impedance Spectro-Tomography Based on Dielectric Relaxation Model [J].

Baidillah, Marlin Ramadhan ;

Iman, Al-Amin Saichul ;

Sun, Yue ;

Takei, Masahiro .

IEEE SENSORS JOURNAL, 2017, 17 (24) :8251-8262

[6]

Barsoukov E, 2005, IMPEDANCE SPECTROSCOPY: THEORY, EXPERIMENT, AND APPLICATIONS, 2ND EDITION, pXII

[7] Effect of magnetic field intensity and γ-Fe2O3 nanoparticle additive on electrical conductivity and viscosity of magnetorheological carbonyl iron suspension-based membranes [J].

Bica, Ioan ;

Anitas, Eugen M. ;

Lu, Qi ;

Choi, Hyoung Jin .

SMART MATERIALS AND STRUCTURES, 2018, 27 (09)

[8] Electrical Impedance Spectroscopy in Skin Cancer Diagnosis [J].

Braun, Ralph P. ;

Mangana, Johanna ;

Goldinger, Simone ;

French, Lars ;

Dummer, Reinhard ;

Marghoob, Ashfaq A. .

DERMATOLOGIC CLINICS, 2017, 35 (04) :489-+

[9] Dielectric Properties for Differentiating Normal and Malignant Thyroid Tissues [J].

Cheng, Yiou ;

Fu, Minghuan .

MEDICAL SCIENCE MONITOR, 2018, 24 :1276-1281

[10] DIFFERENTIAL SCANNING CALORIMETRIC STUDY OF STABILITY OF EGG-WHITE TO HEAT DENATURATION [J].

DONOVAN, JW ;

MAPES, CJ ;

DAVIS, JG ;

GARIBALDI, JA .

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 1975, 26 (01) :73-83

← 1 2 3 →