Fluidic Assembly of Multilayered Tubular Microstructures inside 2-layered Microfluidic Devices

被引：0

作者：

Yue, Tao ^{[1
]}

Nakajima, Masahiro ^{[1
]}

Hu, Chengzhi ^{[1
]}

Takeuchi, Masaru ^{[1
]}

Fukuda, Toshio ^{[1
]}

机构：

[1] Nagoya Univ, Dept Micronano Syst Engn, Chikusa Ku, Nagoya, Aichi 4648603, Japan

来源：

2013 INTERNATIONAL SYMPOSIUM ON MICRO-NANOMECHATRONICS AND HUMAN SCIENCE (MHS) | 2013年

关键词：

FLOW LITHOGRAPHY;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Microfluidic devices provide efficient approaches for building bio-mimetic tubular structures for in vitro tissue models. In this paper, we report a novel method of constructing multilayered tubular structures embedding cells via a 2-layer microfluidic device. The on-chip fabrication of movable microstructures embedding fibroblasts (NIH/3T3) based on Poly (ethylene glycol) Diacrylate (PEGDA) was reported. A novel 2-layered microfluidic device was fabricated by Polydimethylsiloxane (PDMS), for conducting the fluidic self-assembly of the movable microstructures. The self-assembly process via this device was demonstrated. For improving the assembly results, a funneled structure was added in the microfluidic device. The improved self-assembly result of constructing multilayered tubular microstructures with high efficiency was demonstrated.

引用

页数：4