Cholesterol toxicity in pancreatic islets from LDL receptor-deficient mice

被引：6

作者：

de Souza, J. C. ^{[1
]}

de Oliveira, C. A. M. ^{[1
]}

Carneiro, E. M. ^{[1
]}

Boschero, A. C. ^{[1
]}

de Oliveira, H. C. F. ^{[1
]}

机构：

[1] Univ Estadual Campinas, UNICAMP, Dept Anat Biol Celular Fisiol & Biofis, Inst Biol, BR-13083862 Campinas, SP, Brazil

来源：

DIABETOLOGIA | 2010年 / 53卷 / 11期

关键词：

Beta cell function; Cholesterol; Insulin secretion; LDL receptor; Pancreatic islets;

D O I：

10.1007/s00125-010-1868-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2461 / 2462

页数：2

共 3 条

[1] Primary hypercholesterolaemia impairs glucose homeostasis and insulin secretion in low-density lipoprotein receptor knockout mice independently of high-fat diet and obesity [J].

Bonfleur, Maria Lucia ;

Vanzela, Emerielle Cristine ;

Ribeiro, Rosane Aparecida ;

Dorighello, Gabriel de Gabriel ;

de Franca Carvalho, Carolina Prado ;

Collares-Buzato, Carla Beatriz ;

Carneiro, Everardo Magalhaes ;

Boschero, Antonio Carlos ;

Franco de Oliveira, Helena Coutinho .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2010, 1801 (02) :183-190

[2] Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes [J].

Cnop, Miriam .

BIOCHEMICAL SOCIETY TRANSACTIONS, 2008, 36 :348-352

[3] Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function in mice [J].

Kruit, J. K. ;

Kremer, P. H. C. ;

Dai, L. ;

Tang, R. ;

Ruddle, P. ;

de Haan, W. ;

Brunham, L. R. ;

Verchere, C. B. ;

Hayden, M. R. .

DIABETOLOGIA, 2010, 53 (06) :1110-1119

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