The role of mucin-type O-glycans in eukaryotic development

被引：56

作者：

Tabak, Lawrence A. ^{[1
]}

机构：

[1] NIDDKD, Sect Biol Chem, NIH, Bethesda, MD 20892 USA

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2010年 / 21卷 / 06期

关键词：

Mucin-type O-glycosylation; Mucins; Glycosyltransferases; UDP-GalNAc:polypeptide; N-acetylgalactosaminyltransferases; O-glycans; POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE; PORCINE SUBMAXILLARY MUCIN; UDP-GALNAC; IGA NEPHROPATHY; DROSOPHILA-MELANOGASTER; LINKED GLYCOSYLATION; SALIVARY MUCINS; NERVOUS-SYSTEM; MOUSE EMBRYOS; C1GALT1; GENE;

D O I：

10.1016/j.semcdb.2010.02.001

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Newly emerging genetic studies have revealed that a subset of the family of glycosyltransferases responsible for the formation of mucin-typeOglycans is essential for normal development. As additional genetic, biochemical and physical tools are developed to interrogate the complex structure and surface location of this under-studied class of carbohydrate, no doubt additional roles will be elucidated. Published by Elsevier Ltd.

引用

页码：616 / 621

页数：6

共 97 条

[1] Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene [J].

Alexander, Warren S. ;

Viney, Elizabeth M. ;

Zhang, Jian-Guo ;

Metcalf, Donald ;

Kauppi, Maria ;

Hyland, Craig D. ;

Carpinelli, Marina R. ;

Stevenson, William ;

Croker, Ben A. ;

Hilton, Adrienne A. ;

Ellis, Sarah ;

Selan, Carly ;

Nandurkar, Harshal H. ;

Goodnow, Christopher C. ;

Kile, Benjamin T. ;

Nicola, Nicos A. ;

Roberts, Andrew W. ;

Hilton, Douglas J. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (44) :16442-16447

[2] Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans [J].

An, Guangyu ;

Wei, Bo ;

Xia, Baoyun ;

McDaniel, J. Michael ;

Ju, Tongzhong ;

Cummings, Richard D. ;

Braun, Jonathan ;

Xia, Lijun .

JOURNAL OF EXPERIMENTAL MEDICINE, 2007, 204 (06) :1417-1429

[3] The Diversity of O-Linked Glycans Expressed during Drosophila melanogaster Development Reflects Stage- and Tissue-specific Requirements for Cell Signaling [J].

Aoki, Kazuhiro ;

Porterfield, Mindy ;

Lee, Samuel S. ;

Dong, Brian ;

Nguyen, Khoi ;

McGlamry, Katherine H. ;

Tiemeyer, Michael .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (44) :30385-30400

[4] N-LINKED GLYCOPROTEIN-BIOSYNTHESIS IN THE DEVELOPING MOUSE EMBRYO [J].

ARMANT, DR ;

KAPLAN, HA ;

LENNARZ, WJ .

DEVELOPMENTAL BIOLOGY, 1986, 113 (01) :228-237

[5]

BENNETT HS, 1963, MORPHOLOGICAL CYTOCH, V11, P14

[6] ATTACHMENT OF HELICOBACTER-PYLORI TO HUMAN GASTRIC EPITHELIUM MEDIATED BY BLOOD-GROUP ANTIGENS [J].

BOREN, T ;

FALK, P ;

ROTH, KA ;

LARSON, G ;

NORMARK, S .

SCIENCE, 1993, 262 (5141) :1892-1895

[7]

BOURRILLON R, 1989, INT REV CYTOL, V116, P257

[8] Nucleotide sugar transporters of the golgi apparatus: From basic science to diseases [J].

Caffaro, Carolina E. ;

Hirschberg, Carlos B. .

ACCOUNTS OF CHEMICAL RESEARCH, 2006, 39 (11) :805-812

[9]

Chen CC, 2008, J CERAM PROCESS RES, V9, P13

[10] Cell surface biology mediated by low affinity multivalent protein-glycan interactions [J].

Collins, BE ;

Paulson, JC .

CURRENT OPINION IN CHEMICAL BIOLOGY, 2004, 8 (06) :617-625

← 1 2 3 4 5 6 7 8 9 10 →