Long-term survival and quality of life of patients with prolonged postoperative intensive care unit stay: Unmasking an apparent success

被引:37
作者
Gaudino, Mario
Girola, Fabiana
Piscitelli, Mariantonietta
Martinelli, Lorenzo
Anselmi, Amedeo
Della Vella, Carmine
Schiavello, Rocco
Possati, Gianfederico
机构
[1] Univ Cattolica Sacro Cuore, Dept Cardiac Surg, Rome, Italy
[2] Univ Cattolica Sacro Cuore, Dept Cardiac Anesthesia, Rome, Italy
关键词
D O I
10.1016/j.jtcvs.2007.04.028
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: Our objective was to evaluate the long-term survival and quality of life of patients who faced a prolonged (> 10 days) postoperative stay in the intensive care unit and were discharged from the hospital. Methods: Among 3125 consecutive patients who underwent cardiac operations in a 5-year period, we prospectively identified 57 who faced a prolonged postoperative intensive care unit stay and were discharged alive from the hospital. Patients were enrolled in a prospective follow-up protocol and evaluated every 6 to 12 months both clinically and instrumentally. Results: Mean intensive care unit stay was 34 +/- 9 days ( range 11-141 days). Follow-up was complete and mean follow-up time was 71 months. Overall survival was 12 (21%) of 57, and the majority of follow-up deaths were cardiac related. Of the surviving patients, only a small minority (4/12) regained full autonomy and returned to their previous lifestyle. Risk factors for prolonged intensive care unit stay were age, New York Heart Association/Canadian Cardiovascular Society class, hypertension, diabetes, low ejection fraction, aortic surgery, preoperative renal failure, nonelective surgery, prolonged cardiopulmonary bypass time, and perioperative use of aortic counterpulsator. Conclusions: Patients who face a prolonged postoperative intensive care unit stay and who were discharged from the hospital have a very poor long-term outcome and even worse quality of life. These data lead to a consideration of the wisdom of using heroic treatment in patients who face a prolonged postoperative intensive care unit stay in view of the dismal clinical results and enormous use of hospital and human resources.
引用
收藏
页码:465 / 469
页数:5
相关论文
共 8 条
[1]   Survival and quality of life after cardiac surgery complicated by prolonged intensive care [J].
Bapat, V ;
Allen, D ;
Young, C ;
Roxburgh, J ;
Ibrahim, M .
JOURNAL OF CARDIAC SURGERY, 2005, 20 (03) :212-217
[2]   Morbidity, mortality, and quality-of-life outcomes of patients requiring ≥14 days of mechanical ventilation [J].
Combes, A ;
Costa, MA ;
Trouillet, JL ;
Baudot, J ;
Mokhtari, M ;
Gibert, C ;
Chastre, J .
CRITICAL CARE MEDICINE, 2003, 31 (05) :1373-1381
[3]   Prolonged intensive care unit stay in cardiac surgery: Risk factors and long-term-survival [J].
Hein, OV ;
Birnbaum, J ;
Wernecke, K ;
England, M ;
Konertz, W ;
Spies, C .
ANNALS OF THORACIC SURGERY, 2006, 81 (03) :880-885
[4]   Quality of life after heart valve surgery with prolonged intensive care [J].
Hellgren, L ;
Ståhle, E .
ANNALS OF THORACIC SURGERY, 2005, 80 (05) :1693-1698
[5]   Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients [J].
Roques, F ;
Nashef, SAM ;
Michel, P ;
Gauducheau, E ;
de Vincentiis, C ;
Baudet, E ;
Cortina, J ;
David, M ;
Faichney, A ;
Gabrielle, F ;
Gams, E ;
Harjula, A ;
Jones, MT ;
Pintor, PP ;
Salamon, R ;
Thulin, L .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 1999, 15 (06) :816-822
[6]   Long-term survival and quality of life in cardiac surgical patients with prolonged intensive care unit length of stay [J].
Williams, MR ;
Wellner, RB ;
Hartnett, EA ;
Thornton, B ;
Kavarana, MN ;
Mahapatra, R ;
Oz, MC ;
Sladen, R .
ANNALS OF THORACIC SURGERY, 2002, 73 (05) :1472-1478
[7]   Risk factors of delayed extubation, prolonged length of stay in the intensive care unit, and mortality in patients undergoing coronary artery bypass graft with fast-track cardiac anesthesia - A new cardiac risk score [J].
Wong, DT ;
Cheng, DCH ;
Kustra, R ;
Tibshirani, R ;
Karski, J ;
Carroll-Munro, J ;
Sandler, A .
ANESTHESIOLOGY, 1999, 91 (04) :936-944
[8]   EFFECT OF CORONARY-ARTERY BYPASS GRAFT-SURGERY ON SURVIVAL - OVERVIEW OF 10-YEAR RESULTS FROM RANDOMIZED TRIALS BY THE CORONARY-ARTERY BYPASS GRAFT-SURGERY TRIALISTS COLLABORATION [J].
YUSUF, S ;
ZUCKER, D ;
PEDUZZI, P ;
FISHER, LD ;
TAKARO, T ;
KENNEDY, JW ;
DAVIS, K ;
KILLIP, T ;
PASSAMANI, E ;
NORRIS, R ;
MORRIS, C ;
MATHUR, V ;
VARNAUSKAS, E ;
CHALMERS, TC .
LANCET, 1994, 344 (8922) :563-570