Epidural electrical stimulation to facilitate locomotor recovery after spinal cord injury

被引：1

作者：

Audet, Johannie ^{[1
]}

Lecomte, Charly G. ^{[1
]}

机构：

[1] Univ Sherbrooke, Fac Med & Hlth Sci, Dept Pharmacol Physiol, Sherbrooke, PQ, Canada

来源：

JOURNAL OF NEUROPHYSIOLOGY | 2021年 / 126卷 / 05期

关键词：

central pattern generator; epidural electrical stimulation; locomotion; neurorehabilitation; spinal cord injury; NEUROMODULATION;

D O I：

10.1152/jn.00261.2021

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Tonic or phasic electrical epidural stimulation of the lumbosacral region of the spinal cord facilitates locomotion and standing in a variety of preclinical models with severe spinal cord injury. However, the mechanisms of epidural electrical stimulation that facilitate sensorimotor functions remain largely unknown. This review aims to address how epidural electrical stimulation interacts with spinal sensorimotor circuits and discusses the limitations that currently restrict the clinical implementation of this promising therapeutic approach.

引用

页码：1751 / 1755

页数：5

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