Liver Transplantation in Swine without Venovenous Bypass

被引：6
作者：
Heuer, M. [1 ]
Reinhardt, R. [1 ]
Kneiseler, G. [2 ,4 ]
Wuerzinger, P. [1 ]
Zou, X. [4 ]
Hua, F. [3 ]
Jian, F. [3 ]
Paul, A. [1 ]
Kaiser, G. M. [1 ]
机构：
[1] Univ Hosp Essen, Dept Gen Visceral & Transplantat Surg, DE-45122 Essen, Germany
[2] Univ Hosp Essen, Dept Gastroenterol & Hepatol, DE-45122 Essen, Germany
[3] Univ Hosp Essen, Dept Nephrol, DE-45122 Essen, Germany
[4] Univ Hosp Essen, Inst Physiol Chem, DE-45122 Essen, Germany
来源：
EUROPEAN SURGICAL RESEARCH | 2010年 / 45卷 / 01期
关键词：
Experimental surgery; Large animal model; Swine; Liver transplantation; Venovenous bypass; New technique; EXPERIMENTAL SURGERY; PIG; INJURY; PRESERVATION; MODEL;
D O I：
10.1159/000318001
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Introduction: A model of orthotopic liver transplantation in swine was developed to investigate an advanced reperfusion approach. Thereby, we consciously disclaim otherwise commonly practiced venovenous bypass during the recipient operation. Material and Methods: Ten liver transplantations were performed according to the described technique without using venovenous bypass. In each swine the observation period was 48 h. Results: All transplantations were carried out after a median cold ischemic time of 307.5 min (295-340); the median warm ischemic time in these cases was 25 min (20-32). Eight of 10 swine survived 48 h after the operation. Conclusion: Orthotopic liver transplantations in the recipient swine are feasible even without using venovenous bypass. Copyright (C) 2010 S. Karger AG, Basel
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收藏
页码：20 / 25
页数：6
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