Applications of protein-based capacitive Biosensors for the detection of heavy-metal ions

被引：0

作者：

Mortari, Alessia ^{[1
]}

Browns, Nigel L. ^{[2
]}

Geczy, Carolyn ^{[3
]}

Coster, Hans G. L. ^{[4
]}

Valenzuela, Stella M. ^{[5
]}

Martin, Donald ^{[5
]}

Csoregi, Elisabeth ^{[1
]}

机构：

[1] Lund Univ, Dept Analyt Chem, POB 124, S-22100 Lund, Sweden

[2] Univ Birmingham, Sch Biol Sci, POB 363, Birmingham B15 2TT, W Midlands, England

[3] Univ New South Wales, Sch Pathol, Sydney, NSW 2052, Australia

[4] Univ Sydney, Sch Chem Biomol Engn, Sydney, NSW, Australia

[5] Univ Technol Sydney, Inst Nanoscale Technol, Sydney, NSW 2007, Australia

来源：

2006 INTERNATIONAL CONFERENCE ON NANOSCIENCE AND NANOTECHNOLOGY, VOLS 1 AND 2 | 2006年

关键词：

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Three different methods of using protein-based capacitive biosensors for the detection of heavy-metal ions are presented. The metal-binding proteins SmtA, S100A12, MerP and four modified MerPs were immobilised as the biorecognition element on self-assembled monolayer-modified gold electrodes. Capacitance was measured using potential square step or electrical impedance spectroscopy. The protein-metal interaction generated changes in capacitance mainly due to a protein conformational change.

引用

页码：304 / +

页数：2

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