Palladium-catalyzed cyanation reactions of thiophene halides

被引：12
|
作者：
Erker, T [1 ]
Nemec, S [1 ]
机构：
[1] Univ Vienna, Inst Pharmaceut Chem, A-1090 Vienna, Austria
来源：
SYNTHESIS-STUTTGART | 2004年 / 01期
关键词：
nitriles; thiophene; palladium; catalysis; cyanation;
D O I：
10.1055/s-2003-42490
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The described method provides an efficient cyanation reaction of thiophene halides using tris(dibenzylidene-acetone)dipalladium(0), 1,1'-bis-(diphenylphosphino)ferrocene) and zinc powder as the catalyst system and Zn(CN)(2) as the cyanide source. Several thiophenes with various substituents are effectively cyanated under these conditions.
引用
收藏
页码：23 / 25
页数：3
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