Old and New Concepts in the Molecular Pathogenesis of Primary Aldosteronism

被引：32

作者：

Prada, Elke Tatjana Aristizabal ^{[1
]}

Burrello, Jacopo ^{[2
]}

Reincke, Martin ^{[1
]}

Williams, Tracy Ann ^{[1
,2
]}

机构：

[1] Klinikum Ludwig Maximilians Univ Munchen, Med Klin & Poliklin 4, Munich, Germany

[2] Univ Turin, Dept Med Sci, Div Internal Med & Hypertens, Turin, Italy

来源：

HYPERTENSION | 2017年 / 70卷 / 05期

基金：

欧洲研究理事会;

关键词：

HYPERALDOSTERONISM TYPE-II; AUTISM SPECTRUM DISORDERS; K+ CHANNEL MUTATIONS; FAMILIAL HYPERALDOSTERONISM; SOMATIC MUTATIONS; KCNJ5; MUTATIONS; POTASSIUM CHANNEL; REMEDIABLE ALDOSTERONISM; RESISTANT HYPERTENSION; MONOCLONAL-ANTIBODIES;

D O I：

10.1161/HYPERTENSIONAHA.117.10111

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

[No abstract available]

引用

页码：875 / +

页数：11

共 89 条

[51] Molecular Heterogeneity in Aldosterone-Producing Adenomas [J].

Nanba, Kazutaka ;

Chen, Andrew X. ;

Omata, Kei ;

Vinco, Michelle ;

Giordano, Thomas J. ;

Else, Tobias ;

Hammer, Gary D. ;

Tomlins, Scott A. ;

Rainey, William E. .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2016, 101 (03) :999-1007

[52] Histopathological Diagnosis of Primary Aldosteronism Using CYP11B2 Immunohistochemistry [J].

Nanba, Kazutaka ;

Tsuiki, Mika ;

Sawai, Kuniko ;

Mukai, Kuniaki ;

Nishimoto, Koshiro ;

Usui, Takeshi ;

Tagami, Tetsuya ;

Okuno, Hiroshi ;

Yamamoto, Tetsuro ;

Shimatsu, Akira ;

Katabami, Takuyuki ;

Okumura, Ataru ;

Kawa, Gen ;

Tanabe, Akiyo ;

Naruse, Mitsuhide .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2013, 98 (04) :1567-1574

[53] Human Adrenocortical Remodeling Leading to Aldosterone-Producing Cell Cluster Generation [J].

Nishimoto, Koshiro ;

Seki, Tsugio ;

Hayashi, Yuichiro ;

Mikami, Shuji ;

Al-Eyd, Ghaith ;

Nakagawa, Ken ;

Morita, Shinya ;

Kosaka, Takeo ;

Oya, Mototsugu ;

Mitani, Fumiko ;

Suematsu, Makoto ;

Kabe, Yasuaki ;

Mukai, Kuniaki .

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY, 2016, 2016

[54] Case Report: Nodule Development From Subcapsular Aldosterone-Producing Cell Clusters Causes Hyperaldosteronism [J].

Nishimoto, Koshiro ;

Seki, Tsugio ;

Kurihara, Isao ;

Yokota, Kenichi ;

Omura, Masao ;

Nishikawa, Tetsuo ;

Shibata, Hirotaka ;

Kosaka, Takeo ;

Oya, Mototsugu ;

Suematsu, Makoto ;

Mukai, Kuniaki .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2016, 101 (01) :6-9

[55] Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands [J].

Nishimoto, Koshiro ;

Tomlins, Scott A. ;

Kuick, Rork ;

Cani, Andi K. ;

Giordano, Thomas J. ;

Hovelson, Daniel H. ;

Liu, Chia-Jen ;

Sanjanwala, Aalok R. ;

Edwards, Michael A. ;

Gomez-Sanchez, Celso E. ;

Nanba, Kazutaka ;

Rainey, William E. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (33) :E4591-E4599

[56] Adrenocortical Zonation in Humans under Normal and Pathological Conditions [J].

Nishimoto, Koshiro ;

Nakagawa, Ken ;

Li, Dan ;

Kosaka, Takeo ;

Oya, Mototsugu ;

Mikami, Shuji ;

Shibata, Hirotaka ;

Itoh, Hiroshi ;

Mitani, Fumiko ;

Yamazaki, Takeshi ;

Ogishima, Tadashi ;

Suematsu, Makoto ;

Mukai, Kuniaki .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2010, 95 (05) :2296-2305

[57] Potassium Channel Mutant KCNJ5 T158A Expression in HAC-15 Cells Increases Aldosterone Synthesis [J].

Oki, Kenji ;

Plonczynski, Maria W. ;

Lam, Milay Luis ;

Gomez-Sanchez, Elise P. ;

Gomez-Sanchez, Celso E. .

ENDOCRINOLOGY, 2012, 153 (04) :1774-1782

[58] Different Expression of 11β-Hydroxylase and Aldosterone Synthase Between Aldosterone-Producing Microadenomas and Macroadenomas [J].

Ono, Yoshikiyo ;

Nakamura, Yasuhiro ;

Maekawa, Takashi ;

Felizola, Saulo J. A. ;

Morimoto, Ryo ;

Iwakura, Yoshitsugu ;

Kudo, Masataka ;

Seiji, Kazumasa ;

Takase, Kei ;

Arai, Yoichi ;

Gomez-Sanchez, Celso E. ;

Ito, Sadayoshi ;

Sasano, Hironobu ;

Satoh, Fumitoshi .

HYPERTENSION, 2014, 64 (02) :438-+

[59] New gain-of-function mutation shows CACNA1D as recurrently mutated gene in autism spectrum disorders and epilepsy [J].

Pinggera, Alexandra ;

Mackenroth, Luisa ;

Rump, Andreas ;

Schallner, Jens ;

Beleggia, Filippo ;

Wollnik, Bernd ;

Striessnig, Joerg .

HUMAN MOLECULAR GENETICS, 2017, 26 (15) :2923-2932

[60] CACNA1D De Novo Mutations in Autism Spectrum Disorders Activate Cav1.3 L-Type Calcium Channels [J].

Pinggera, Alexandra ;

Lieb, Andreas ;

Benedetti, Bruno ;

Lampert, Michaela ;

Monteleone, Stefania ;

Liedl, Klaus R. ;

Tuluc, Petronel ;

Striessnig, Joerg .

BIOLOGICAL PSYCHIATRY, 2015, 77 (09) :816-822

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