Combined effect of body mass index and waist-height ratio on incident diabetes; a population based cohort study

被引：22

作者：

Mitsuhashi, Kazuteru ^{[1
]}

Hashimoto, Yoshitaka ^{[1
]}

Tanaka, Muhei ^{[1
]}

Toda, Hitoshi ^{[2
]}

Matsumoto, Shinobu ^{[1
]}

Ushigome, Emi ^{[1
]}

Asano, Mai ^{[1
]}

Yamazaki, Masahiro ^{[1
]}

Oda, Yohei ^{[1
]}

Fukui, Michiaki ^{[1
]}

机构：

[1] Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Endocrinol & Metab, Kamigyo Ku, 465 Kajii Cho, Kyoto 6028566, Japan

[2] Oike Clin, Dept Internal Med, Nakagyo Ku, 11 Shimoai Cho, Kyoto 6048436, Japan

来源：

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION | 2017年 / 61卷 / 02期

关键词：

obesity; body mass index; type; 2; diabetes; abdominal obesity; waist circumference; METABOLICALLY HEALTHY OBESITY; FAT DISTRIBUTION; RISK-FACTORS; INSULIN SENSITIVITY; SCREENING TOOL; WEIGHT-GAIN; INDICATOR; LIVER; MEN; CIRCUMFERENCE;

D O I：

10.3164/jcbn.16-116

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

We investigated the impact of combined effect of body mass index and waist-to-height ratio on risk of diabetes. Overweight and abdominal obesity were defined as body mass index >= 23 kg/m(2) and waist-to-height ratio >= 0.5, respectively. We divided participants into four groups according to presence of overweight and/or abdominal obesity. About 20% individuals with overweight did not complicated with an abdominal obesity. Among 3,737 participants, 286 participants had diabetes at baseline-examination. Adjusted odds ratios for prevalence of diabetes compared with non overweight participants without abdominal obesity were as follow: 1.87 (95% confidence interval 1.09-3.14, p = 0.024) in non overweight participants with abdominal obesity, 1.51 (0.87-2.55, p = 0.141) in overweight participants without abdominal obesity and 3.25 (2.37-4.52, p<0.001) in overweight participants with abdominal obesity. In the follow-up examination, 86 participants were diagnosed as diabetes among 2,263 participants. Adjusted odds ratios for incident diabetes were as follow: 2.59 (0.98-6.44, p = 0.056) in non-overweight participants with abdominal obesity, 1.65 (0.64-4.00, p = 0.288) in overweight participants without abdominal obesity and 2.77 (1.55-5.15, p<0.001) in overweight participants with abdominal obesity. Non-overweight individuals with abdominal obesity as well as overweight individuals with abdominal obesity was associated with diabetes compared with non-overweight individuals without abdominal obesity.

引用

页码：118 / 122

页数：5

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