EXERCISE PRECONDITIONING AND BRAIN ISCHEMIC TOLERANCE

被引：100
|
作者：
Zhang, F. [1 ,2 ]
Wu, Y. [1 ,2 ]
Jia, J. [1 ,2 ]
机构：
[1] Fudan Univ, Huashan Hosp, Dept Rehabil, Shanghai 200040, Peoples R China
[2] Fudan Univ, Coll Med, Dept Sports Med & Rehabil, Shanghai 200032, Peoples R China
来源：
NEUROSCIENCE | 2011年 / 177卷
关键词：
exercise preconditioning; brain ischemic tolerance; inflammatory response; neuron apoptosis; blood-brain barrier; cerebral vasculature; FOCAL CEREBRAL-ISCHEMIA; PHYSICAL-ACTIVITY; HIPPOCAMPAL CA1; BARRIER DYSFUNCTION; NEURONAL APOPTOSIS; ARTERY OCCLUSION; PROGENITOR CELLS; STROKE RISK; TNF-ALPHA; IN-VIVO;
D O I：
10.1016/j.neuroscience.2011.01.018
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
It is well established that physical exercise can exert neuroprotection both in clinical settings and animal experiments. A series of studies have demonstrated that physical exercise may be a promising preconditioning method to induce brain ischemic tolerance through the promotion of angiogenesis, mediation of the inflammatory response, inhibition of glutamate over-activation, protection of the blood brain barrier (BBB) and inhibition of apoptosis. Through these mechanisms, exercise preconditioning may reduce the neural deficits associated with ischemia and the development of brain infarction and thus provide brain ischemic tolerance. An awareness of the benefits of exercise preconditioning may lead more patients to accept exercise therapy in cases of ischemic stroke. (C) 2011 IBRO. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：170 / 176
页数：7
相关论文
共 50 条
  • [21] Upregulation of TACE/ADAM17 after ischemic preconditioning is involved in brain tolerance
    Cárdenas, A
    Moro, MA
    Leza, JC
    O'Shea, E
    Dávalos, A
    Castillo, J
    Lorenzo, P
    Lizasoain, I
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2002, 22 (11): : 1297 - 1302
  • [22] Neuroproctective Effects of Ischemic Tolerance (Preconditioning) and Postconditioning
    Alkan, Tulin
    TURKISH NEUROSURGERY, 2009, 19 (04) : 406 - 412
  • [23] Ischemic Tolerance in an In Vivo Model of Glutamate Preconditioning
    Badawi, Yomna
    Pal, Ranu
    Hui, Dongwei
    Michaelis, Elias K.
    Shi, Honglian
    JOURNAL OF NEUROSCIENCE RESEARCH, 2015, 93 (04) : 623 - 632
  • [24] Ischemic preconditioning protects against ischemic brain injury
    Xiao-meng Ma
    Mei Liu
    Ying-ying Liu
    Li-li Ma
    Ying Jiang
    Xiao-hong Chen
    NeuralRegenerationResearch, 2016, 11 (05) : 765 - 770
  • [25] Ischemic preconditioning protects against ischemic brain injury
    Ma, Xiao-meng
    Liu, Mei
    Liu, Ying-ying
    Ma, Li-li
    Jiang, Ying
    Chen, Xiao-hong
    NEURAL REGENERATION RESEARCH, 2016, 11 (05) : 765 - 770
  • [26] Resveratrol mimics ischemic preconditioning in the brain
    Raval, Ami P.
    Dave, Kunjan R.
    Perez-Pinzon, Miguel A.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2006, 26 (09): : 1141 - 1147
  • [27] The neuroprotective mechanism of brain ischemic preconditioning
    Xiao-qian Liu
    Rui Sheng
    Zheng-hong Qin
    Acta Pharmacologica Sinica, 2009, 30 : 1071 - 1080
  • [28] The Effects of Ischemic Preconditioning on Human Exercise Performance
    Incognito, Anthony V.
    Burr, Jamie F.
    Millar, Philip J.
    SPORTS MEDICINE, 2016, 46 (04) : 531 - 544
  • [29] The neuroprotective mechanism of brain ischemic preconditioning
    Liu, Xiao-qian
    Sheng, Rui
    Qin, Zheng-hong
    ACTA PHARMACOLOGICA SINICA, 2009, 30 (08) : 1071 - 1080
  • [30] Non ischemic myocardial preconditioning by tachycardia and exercise
    Domenech, R
    Macho, P
    Sánchez, G
    Donoso, P
    MYOCARDIAL ISCHEMIA AND PRECONDITIONING, 2003, 6 : 365 - 371
12345