Efficacy of Oral Hydration in the Prevention of Contrast-Induced Acute Kidney Injury in Patients Undergoing Coronary Angiography or Intervention

被引:23
作者
Akyuz, Sukru [1 ]
Karaca, Mehmet [1 ]
Oz, Tugba Kemaloglu [1 ]
Altay, Servet [1 ]
Gungor, Baris [1 ]
Yaylak, Baris [3 ]
Yazici, Selcuk [1 ]
Ozden, Kivilcim [1 ]
Karakus, Gultekin [2 ]
Cam, Nese [1 ]
机构
[1] Siyami Ersek Thorac & Cardiovasc Surg Training &, Dept Cardiol, Diyarbakir, Turkey
[2] Acibadem Maslak Hosp, Dept Cardiol, Istanbul, Turkey
[3] Diyarbakir Training & Res Hosp, Dept Cardiol, Diyarbakir, Turkey
来源
NEPHRON CLINICAL PRACTICE | 2014年 / 128卷 / 1-2期
关键词
Acute kidney injury; Contrast media; Coronary angiography; Percutaneous coronary intervention; COMPUTED-TOMOGRAPHY ANGIOGRAPHY; INDUCED NEPHROPATHY; INTRAVENOUS HYDRATION; SALINE HYDRATION; RANDOMIZED-TRIAL; RENAL-FAILURE; RISK; PREDICTION;
D O I
10.1159/000365090
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Background: Efficacy of intravenous (IV) volume expansion in preventing contrast-induced acute kidney injury (CI-AKI) is well known. However, the role of oral hydration has not been well established. The aim of this work was to evaluate the efficacy of oral hydration in preventing CI-AKI. Methods: We prospectively randomized 225 patients undergoing coronary angiography and/or percutaneous coronary intervention in either oral hydration or IV hydration groups. Patients who have at least one of the high-risk factors for developing CI-AKI (advanced age, type 2 diabetes mellitus, anemia, hyperuricemia, a history of cardiac failure or systolic dysfunction) were included in the study. All patients had normal renal function or stage 1-2 chronic kidney disease. Patients in the oral hydration group were encouraged to drink unrestricted amounts of fluids freely whereas isotonic saline infusion was performed by the standard protocol in the IV hydration group. Results: CI-AKI occurred in 8/116 patients (6.9%) in the oral hydration group and 8/109 patients (7.3%) in the IV hydration group (p = 0.89). There was also no statistically significant difference between the two groups when different CI-AKI definitions were taken into account. Conclusion: Oral hydration is as effective as IV hydration in preventing CI-AKI in patients with normal kidney function or stage 1-2 chronic kidney disease, and who also have at least one of the other high-risk factors for developing CI-AKI. (C) 2014 S. Karger AG, Basel
引用
收藏
页码:95 / 100
页数:6
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