Fabrication and magnetic control of bacteria-inspired robotic microswimmers

被引：65

作者：

Cheang, U. Kei ^{[1
]}

Roy, Dheeraj ^{[2
]}

Lee, Jun Hee ^{[1
,3
]}

Kim, Min Jun ^{[1
,2
]}

机构：

[1] Drexel Univ, Dept Mech Engn & Mech, Philadelphia, PA 19104 USA

[2] Drexel Univ, Sch Biomed Engn Sci & Hlth Syst, Philadelphia, PA 19104 USA

[3] Korea Inst Machinery & Mat, Nano Convergence & Mfg Syst Res Div, Taejon 305343, South Korea

来源：

APPLIED PHYSICS LETTERS | 2010年 / 97卷 / 21期

基金：

美国国家科学基金会;

关键词：

MICROROBOTS;

D O I：

10.1063/1.3518982

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

A biomimetic, microscale system using the mechanics of swimming bacteria has been fabricated and controlled in a low Reynolds number fluidic environment. The microswimmer consists of a polystyrene microbead conjugated to a magnetic nanoparticle via a flagellar filament using avidin-biotin linkages. The flagellar filaments were isolated from the bacterium, Salmonella typhimurium. Propulsion energy was supplied by an external rotating magnetic field designed in an approximate Helmholtz configuration. Further, the finite element analysis software, COMSOL MULTIPHYSICS, was used to develop a simulation of the robotic devices within the magnetic controller. The robotic microswimmers exhibited flagellar propulsion in two-dimensional magnetic fields, which demonstrate controllability of the biomimetically designed devices for future biomedical applications. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3518982]

引用

页数：3

共 13 条

[1] Dumbbell diffusion in a spatially periodic potential [J].

Bammert, Jochen ;

Schreiber, Steffen ;

Zimmermann, Walter .

PHYSICAL REVIEW E, 2008, 77 (04)

[2] Bacterial flagella-based propulsion and on/off motion control of microscale objects [J].

Behkam, Bahareh ;

Sitti, Metin .

APPLIED PHYSICS LETTERS, 2007, 90 (02)

[3]

Behkam B, 2007, LECT NOTES ARTIF INT, V4850, P154

[4] The rotary motor of bacterial flagella [J].

Berg, HC .

ANNUAL REVIEW OF BIOCHEMISTRY, 2003, 72 :19-54

[5]

BERG HC, 1973, NATURE, V245, P380, DOI 10.1038/245380a0

[6]

Darnton N, 2004, BIOPHYS J, V86, p160A

[7]

DIAMANDIS EP, 1991, CLIN CHEM, V37, P625

[8] Microscopic artificial swimmers [J].

Dreyfus, R ;

Baudry, J ;

Roper, ML ;

Fermigier, M ;

Stone, HA ;

Bibette, J .

NATURE, 2005, 437 (7060) :862-865

[9]

ISHIYAMA K, 2000, 2000 INT S MICR HUM, P65

[10] Brownian dynamics of a microswimmer [J].

Lobaskin, V. ;

Lobaskin, D. ;

Kulic, I. M. .

EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS, 2008, 157 (1) :149-156

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