Vena Cava Filter Retrieval Rates and Factors Associated With Retrieval in a Large US Cohort

被引:56
作者
Brown, Joshua D. [1 ,2 ]
Raissi, Driss [3 ]
Han, Qiong [3 ]
Adams, Val R. [1 ]
Talbert, Jeffery C. [1 ]
机构
[1] Univ Kentucky, Coll Pharm, Dept Pharm Practice & Sci, Lexington, KY USA
[2] Univ Florida, Coll Pharm, Dept Pharmaceut Outcomes & Policy, Gainesville, FL USA
[3] Univ Kentucky, Coll Med, Dept Radiol, Div Vasc & Intervent Radiol, Lexington, KY USA
来源
JOURNAL OF THE AMERICAN HEART ASSOCIATION | 2017年 / 6卷 / 09期
基金
美国国家卫生研究院;
关键词
pulmonary embolism; retrieval device; vena cava; vena cava filter; venous thromboembolism; VENOUS THROMBOEMBOLISM; PULMONARY-EMBOLISM; INTERVENTIONAL-RADIOLOGY; ADMINISTRATIVE DATA; TRAUMA; PREVENTION; GUIDELINES; SOCIETY; POPULATION; HOSPITALS;
D O I
10.1161/JAHA.117.006708
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background-Retrieval of vena cava filters (VCFs) is important for safety as complications increase with longer dwell times. This study assessed VCF retrieval rates and factors associated with retrieval in a national cohort. Methods and Results-VCFs were identified by procedural codes from an administrative claims database. Patients were identified who had a VCF placement during a hospitalization from a national commercial administrative claims database. Indications for VCF placement were identified as pulmonary embolism with or without deep vein thrombosis, deep vein thrombosis only, or prophylactic. Patient demographic and clinical characteristics were included in proportional hazard regression models to find associations with early (90-day) and 1-year VCF retrieval. Initiation of anticoagulation and the correlation between time-to-retrieval and time-to-initiation of anticoagulation were observed. Of 54 766 patients receiving a VCF, 36.9% had pulmonary embolism, 43.9% had deep vein thrombosis only, and 19.2% had no apparent venous thromboembolism present. Over the 1 year of follow-up, the cumulative incidence of VCF retrieval was 18.4%. Retrieval increased over time from a low of 14.0% in 2010 up to approximate to 24% in 2014. In adjusted time-to-event models, increasing age, differing regions, and some comorbidities were associated with poorer retrieval rates. Initiation of anticoagulation was poorly correlated with retrieval, with anticoagulation preceding retrieval by a median of 51 days while those without retrieval had a median of 278 days of exposure to anticoagulation. Conclusions-VCF retrieval increased over the study period but remained suboptimal and was weakly correlated with anticoagulation initiation.
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页数:11
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